miR‐218 regulates diabetic nephropathy via targeting IKK‐β and modulating NK‐κB‐mediated inflammation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29224
Abstract: Diabetic nephropathy (DN) is a common clinically relevant complication of diabetes that is associated with damage to the capillaries, yet the etiology of this condition remains unclear. Nuclear factor‐kappa B (NF‐κB) activation is known to… read more here.
Keywords: mediated inflammation; mir 218; progression; diabetic nephropathy ... See more keywords
Enhanced eosinophil-mediated inflammation associated with antibody and complement-dependent pneumonic insults in critical COVID-19
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DOI: 10.1016/j.celrep.2021.109798
Abstract: Despite the worldwide effect of the Coronavirus disease 2019 (COVID-19) pandemic, the underlying mechanisms of fatal viral pneumonia remain elusive. Here, we show that critical COVID-19 is associated with enhanced eosinophil-mediated inflammation when compared to… read more here.
Keywords: eosinophil mediated; mediated inflammation; covid; critical covid ... See more keywords
Paeonol inhibits NLRP3 mediated inflammation in rat endothelial cells by elevating hyperlipidemic rats plasma exosomal miRNA-223.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173473
Abstract: Atherosclerosis (AS) is a multifactorial chronic inflammatory disease, and hyperlipidemia is the important factors leading to AS, which can cause vascular endothelial dysfunction. Paeonol (Pae) is a potential therapeutic drug for AS, and we have… read more here.
Keywords: elevating hyperlipidemic; rats plasma; mediated inflammation; hyperlipidemic rats ... See more keywords
Inflammasome‐mediated Inflammation by Malassezia in human keratinocytes: A comparative analysis with different strains
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DOI: 10.1111/myc.13214
Abstract: Malassezia species are associated with several common dermatologic conditions including pityriasis versicolor, seborrhoeic dermatitis, folliculitis, and atopic dermatitis and dandruff. However, its causal role remains to be established. We intended to explore the role of… read more here.
Keywords: malassezia; different malassezia; malassezia species; mediated inflammation ... See more keywords
Andrographolide Ameliorates Diabetic Cardiomyopathy in Mice by Blockage of Oxidative Damage and NF-κB-Mediated Inflammation
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DOI: 10.1155/2018/9086747
Abstract: Andrographolide (Andro), a major bioactive component obtained from Andrographis paniculata Nees, has exerted wide antioxidant as well as cytoprotective properties. However, whether Andro treatment could retard the progress of diabetic cardiomyopathy (DCM) remains unknown. In… read more here.
Keywords: mediated inflammation; inflammation; mice; diabetic cardiomyopathy ... See more keywords
Paeoniflorin Attenuated TREM-1-Mediated Inflammation in THP-1 Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Healthcare Engineering"
DOI: 10.1155/2022/7051643
Abstract: Sepsis is caused by bacterial infections or viral infections. Clinically, there exist confirmed or highly suspected infection foci. Mortality caused by septic shock remains in a high rate even though antibiotic treatment works effectively. In… read more here.
Keywords: trem mediated; mediated inflammation; thp cells; paeoniflorin ... See more keywords
Mechanisms and Therapeutic Modulation of Neutrophil-Mediated Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Dental Research"
DOI: 10.1177/00220345221107602
Abstract: Neutrophils are abundant, short-lived myeloid cells that are readily recruitable to sites of inflammation, where they serve as first-line defense against infection and other types of insult to the host. In recent years, there has… read more here.
Keywords: inflammation; mechanisms therapeutic; neutrophil mediated; therapeutic modulation ... See more keywords
Association between the type of allergen and T-helper 2 mediated inflammation in allergic reactions: a systematic review and a meta-analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v50i1.470
Abstract: OBJECTIVES To determine whether the levels of T-helper (TH) 2 cytokines (interleukin (IL)-4 and IL-5) in allergic reactions are allergen dependent and evaluate the impact of various treatment strategies on the levels of these cytokines.… read more here.
Keywords: mediated inflammation; inflammation; inflammation allergic; type allergen ... See more keywords
Inhibitory effects of luteolin on TLR3-mediated inflammation caused by TAK/NF-κB signaling in human corneal fibroblasts.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2022.03.01
Abstract: AIM To study the role of luteolin (LUT) in the expression of toll-like receptors 3 (TLR3) ligand polyI:C stimulated inflammatory factors in human corneal fibroblasts (HCFs). METHODS HCFs cells were cultivated with or without LUT… read more here.
Keywords: mediated inflammation; human corneal; expression; factor ... See more keywords
Reactive Oxygen Species-Mediated Inflammation and Apoptosis in Hand-Foot Syndrome Induced by PEGylated Liposomal Doxorubicin [Corrigendum]
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s354929
Abstract: [This corrects the article DOI: 10.2147/IJN.S280187.]. read more here.
Keywords: species mediated; inflammation apoptosis; mediated inflammation; apoptosis hand ... See more keywords
p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2017.00271
Abstract: Japanese encephalitis virus (JEV) targets central nervous system, resulting in neuroinflammation with typical features of neuronal death along with hyper activation of glial cells. Exploring the mechanisms responsible for the JEV-caused inflammatory response remains a… read more here.
Keywords: encephalitis virus; jev; mediated inflammation; japanese encephalitis ... See more keywords