TICAM-1 is dispensable in STING-mediated innate immune responses in myeloid immune cells.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.04.035
Abstract: Stimulator of interferon genes (STING) is an essential molecule for the production of type I interferon (IFN), and other inflammatory cytokines, in response to cytosolic DNA. STING contributes to host defense against infection and anti-tumor… read more here.
Keywords: innate immune; mediated innate; immune responses; sting mediated ... See more keywords
African swine fever virus I267L acts as an important virulence factor by inhibiting RNA polymerase III-RIG-I-mediated innate immunity
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010270
Abstract: ASFV is a large DNA virus that is highly pathogenic in domestic pigs. How this virus is sensed by the innate immune system as well as why it is so virulent remains enigmatic. In this… read more here.
Keywords: rna polymerase; iii; rig mediated; iii rig ... See more keywords
Viruses utilize ubiquitination systems to escape TLR/RLR-mediated innate immunity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1065211
Abstract: When the viruses invade the body, they will be recognized by the host pattern recognition receptors (PRRs) such as Toll like receptor (TLR) or retinoic acid-induced gene-I like receptor (RLR), thus causing the activation of… read more here.
Keywords: rlr mediated; rlr; tlr rlr; innate immunity ... See more keywords
Editorial: Updates on RIG-I-like receptor-mediated innate immune responses
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1153410
Abstract: COPYRIGHT © 2023 Kishore and Kufer. This is an openaccess article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the… read more here.
Keywords: receptor mediated; updates rig; like receptor; editorial updates ... See more keywords
TRIMming Type I Interferon-Mediated Innate Immune Response in Antiviral and Antitumor Defense
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13020279
Abstract: The tripartite motif (TRIM) family comprises at least 80 members in humans, with most having ubiquitin or SUMO E3 ligase activity conferred by their N-terminal RING domain. TRIMs regulate a wide range of processes in… read more here.
Keywords: antiviral antitumor; response; mediated innate; immune response ... See more keywords