Antimicrobial effect of pimozide by targeting ROS-mediated killing in Staphylococcus aureus.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2465
Abstract: In spite of the higher nosocomial and community-acquired infections acquired by Staphylococcus aureus, emerging drug resistance is a leading cause of increased mortality and morbidity associated with the overuse of antimicrobials. It is an emergent… read more here.
Keywords: effect; pmz; effect pimozide; staphylococcus aureus ... See more keywords
Method development for the analysis of PBMC-mediated killing of K562 cells by bovine colostrum.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2021.113175
Abstract: BACKGROUND Colostrum is the first milk that supplies newborns with immune supporting peptides. Due to its heterogeneous and variable characteristics, standardized assays for assessment of its biological activities are a challenge. The current set of… read more here.
Keywords: bovine colostrum; mediated killing; k562 cells; killing k562 ... See more keywords
The Role of Reactive Oxygen Species in Antibiotic-Mediated Killing of Bacteria.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in microbiology"
DOI: 10.1016/j.tim.2016.12.008
Abstract: Recently, it was proposed that there is a common mechanism behind the activity of bactericidal antibiotics, involving the production of reactive oxygen species (ROS). However, the involvement of ROS in antibiotic-mediated killing has become the… read more here.
Keywords: reactive oxygen; role reactive; oxygen species; antibiotic mediated ... See more keywords
A brain-enriched lncRNA shields cancer cells from immune-mediated killing for metastatic colonization in the brain
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2200230119
Abstract: Significance Brain metastasis with current limited treatment options is a common complication in advanced cancer patients, and breast-to-brain metastasis (B2BM) is one of the major types. In this work, we report that brain metastasis oncogenic… read more here.
Keywords: immune mediated; brain; mediated killing; brain metastasis ... See more keywords
Serum IgM and C-Reactive Protein Binding to Phosphorylcholine of Nontypeable Haemophilus influenzae Increases Complement-Mediated Killing
Sign Up to like & getrecommendations! Published in 2019 at "Infection and Immunity"
DOI: 10.1128/iai.00299-19
Abstract: Nontypeable Haemophilus influenzae (NTHi) colonizes the human upper respiratory tract without causing disease symptoms, but it is also a major cause of upper and lower respiratory tract infections in children and elderly, respectively. NTHi synthesizes… read more here.
Keywords: mediated killing; igm; pcho; complement mediated ... See more keywords
Nitrite Promotes ROS Production to Potentiate Cefoperazone-Sulbactam-Mediated Elimination to Lab-Evolved and Clinical-Evolved Pseudomonas aeruginosa
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02327-21
Abstract: Antibiotic-resistant Pseudomonas aeruginosa has become a real concern in hospital-acquired infections, especially in critically ill and immunocompromised patients. Understanding antibiotic resistance mechanisms and developing novel control measures are highly appreciated. ABSTRACT Cefoperazone-sulbactam (SCF)-resistant Pseudomonas aeruginosa… read more here.
Keywords: evo; pseudomonas aeruginosa; scf; mediated killing ... See more keywords
Tissue Dimensionality Influences the Functional Response of Cytotoxic T Lymphocyte-Mediated Killing of Targets
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2016.00668
Abstract: Cytotoxic T lymphocyte (CTL)-mediated killing of virus infections and tumors occurs over a wide range of conditions. The spatial environments in which CTLs encounter target cells vary from narrow vessels, to two-dimensional epithelial tissues, to… read more here.
Keywords: response; tissue dimensionality; cytotoxic lymphocyte; functional response ... See more keywords
How Escherichia coli Circumvent Complement-Mediated Killing
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00452
Abstract: Complement is a crucial arm of the innate immune response against invading bacterial pathogens, and one of its main functions is to recognize and destroy target cells. Similar to other pathogens, Escherichia coli has evolved… read more here.
Keywords: escherichia coli; coli circumvent; circumvent complement; complement ... See more keywords
New insights into CAR T cell-mediated killing of tumor cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1016208
Abstract: Adoptive transfer of T cells genetically engineered to express chimeric antigen receptors (CAR) has demonstrated striking efficacy for the treatment of several hematological malignancies, including B-cell lymphoma, leukemia, and multiple myeloma. However, CAR T-cell efficacy… read more here.
Keywords: cell; car; mediated killing; car cell ... See more keywords