Nanomaterial-wrapped dsCYP15C1, a potential RNAi-based strategy for pest control against Chilo suppressalis.
Sign Up to like & getrecommendations! Published in 2020 at "Pest management science"
DOI: 10.1002/ps.5789
Abstract: BACKGROUND Although the utility of dsRNA-mediated knockdown as an environmentally friendly pest management strategy has gained traction in recent years, its overall efficacy has been limited by poor stability and limited cellular uptake. The encapsulation… read more here.
Keywords: chilo suppressalis; rnai; mediated knockdown; strategy ... See more keywords
RNAi-mediated knockdown of MCM7 gene on CML cells and its therapeutic potential for leukemia
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DOI: 10.1007/s12032-016-0878-x
Abstract: MCM7 is one of the subunits of MCM2-7 complex, which is essential to DNA replication licensing and the control of cell cycle progression. It has been demonstrated that MCM7 participates in mRNA transcription and DNA… read more here.
Keywords: mcm7 gene; mediated knockdown; rnai mediated; gene ... See more keywords
RNAi-Mediated Knockdown of Transcription Factor E93 in Nymphs of the Desert Locust (Schistocerca gregaria) Inhibits Adult Morphogenesis and Results in Supernumerary Juvenile Stages
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DOI: 10.3390/ijms21207518
Abstract: Postembryonic development of insects is coordinated by juvenile hormone (JH) together with ecdysteroids. Whereas the JH early response gene krüppel-homolog 1 (Kr-h1) plays a crucial role in the maintenance of juvenile characteristics during consecutive larval… read more here.
Keywords: desert locust; adult morphogenesis; locust schistocerca; mediated knockdown ... See more keywords
Peptidomimetic Lipid-Nanoparticle-Mediated Knockdown of TLR4 in CNS Protects against Cerebral Ischemia/Reperfusion Injury in Mice
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DOI: 10.3390/nano12122072
Abstract: Ischemic stroke activates toll-like receptor 4 (TLR4) signaling, resulting in proinflammatory polarization of microglia and secondary neuronal damage. Herein, we report a novel lipid-nanoparticle (LNP)-mediated knockdown of TLR4 in microglia and amelioration of neuroinflammation in… read more here.
Keywords: knockdown tlr4; cns; lipid nanoparticle; mice ... See more keywords