A Case of Immune‐Mediated Liver Injury Induced by Olaparib
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.30119
Abstract: Immune-mediated drug-induced liver injury (IM-DILI) can be triggered by biologic agents, in addition to traditional drugs, including statins, minocycline, and nitrofurantoin. IM-DILI may be indistinguishable at presentation from autoimmune hepatitis (AIH) and cessation of the… read more here.
Keywords: case immune; injury induced; immune mediated; liver injury ... See more keywords
Glycyrrhizin mediated liver-targeted alginate nanogels delivers quercetin to relieve acute liver failure.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.11.204
Abstract: Acute liver failure is an uncommon and dramatic clinical syndrome with a high risk of mortality. Previous treatments existed some limitations of poor bioavailability and targeting the efficiency of drugs. In this study, a novel… read more here.
Keywords: glycyrrhizin mediated; liver failure; acute liver; mediated liver ... See more keywords
Cellular therapies for the treatment of immune-mediated GI and liver disease.
Sign Up to like & getrecommendations! Published in 2020 at "British medical bulletin"
DOI: 10.1093/bmb/ldaa035
Abstract: INTRODUCTION Immune-mediated liver and gastrointestinal diseases are chronic conditions that lack curative treatments. Despite advances in the understanding and treatment of these conditions, they frequently remain refractory to treatment and represent a significant unmet need.… read more here.
Keywords: immune; treatment; clinical trials; immune mediated ... See more keywords
RAGE: A potential therapeutic target during FGF1 treatment of diabetes‐mediated liver injury
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16446
Abstract: As a serious metabolic disease, diabetes causes series of complications that seriously endanger human health. The liver is a key organ for metabolizing glucose and lipids, which substantially contributes to the development of insulin resistance… read more here.
Keywords: diabetes mediated; fgf1 treatment; treatment; rage ... See more keywords
Berbamine and thymoquinone exert protective effects against immune-mediated liver injury via NF-κB dependent pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.960981
Abstract: Background Immune-mediated hepatitis is a severe impendence to human health, and no effective treatment is currently available. Therefore, new, safe, low-cost therapies are desperately required. Berbamine (BE), a natural substance obtained primarily from Berberis vulgaris… read more here.
Keywords: mediated liver; day; immune mediated; liver injury ... See more keywords
The Autophagy Pathway: A Critical Route in the Disposal of Alpha 1-Antitrypsin Aggregates That Holds Many Mysteries
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041875
Abstract: The maintenance of proteome homeostasis, or proteostasis, is crucial for preserving cellular functions and for cellular adaptation to environmental challenges and changes in physiological conditions. The capacity of cells to maintain proteostasis requires precise control… read more here.
Keywords: liver disease; aatd mediated; alpha antitrypsin; mediated liver ... See more keywords