Negative DNA supercoiling makes protein-mediated looping deterministic and ergodic within the bacterial doubling time
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DOI: 10.1093/nar/gkab946
Abstract: Abstract Protein-mediated DNA looping is fundamental to gene regulation and such loops occur stochastically in purified systems. Additional proteins increase the probability of looping, but these probabilities maintain a broad distribution. For example, the probability… read more here.
Keywords: protein; protein mediated; mediated looping; dna ... See more keywords