The Fyn-Stat5 cascade is required for Fcγ receptor-mediated mast cell function.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2020.104134
Abstract: Mast cells, well established effectors in allergic disease, can be activated by numerous stimuli. We previously found that the Fyn-Stat5B pathway is critical for FcεRI-stimulated mast cell function. Because IgG receptors employ similar signaling pathways,… read more here.
Keywords: mediated mast; mast; stat5b; mast cell ... See more keywords
Peptide‐mediated mast cell activation: ligand similarities for receptor recognition and protease‐induced regulation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Leukocyte Biology"
DOI: 10.1189/jlb.3ru1216-539r
Abstract: MCs are crucial regulators of the innate immune response. MC degranulation is a rapid response mechanism that allows for the release of a stored plethora of inflammatory mediators, including histamine, heparin, various serine proteases, chemokines,… read more here.
Keywords: mediated mast; peptide mediated; peptide stimuli; cell activation ... See more keywords