Emerging mitochondrial‐mediated mechanisms involved in oligodendrocyte development
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25151
Abstract: Oligodendrocytes are the myelinating glia of the central nervous system and are generated after oligodendrocyte progenitor cells (OPCs) transition into pre‐oligodendrocytes and then into myelinating oligodendrocytes. Myelin is essential for proper signal transmission within the… read more here.
Keywords: development; oligodendrocyte development; mediated mechanisms; mitochondrial mediated ... See more keywords
Microbiome-mediated mechanisms contributing to the environmental tolerance of reef invertebrate species
Sign Up to like & getrecommendations! Published in 2021 at "Marine Biology"
DOI: 10.1007/s00227-021-03893-0
Abstract: Coral reefs globally are increasingly impacted by climate change. High temperature and pCO2 levels disrupt multiple physiological and biochemical pathways in marine organisms, often leading to disease and mortality in sensitive reef species. Host-associated microbes… read more here.
Keywords: microbiome mediated; mediated mechanisms; invertebrate species; reef ... See more keywords
Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological Reports"
DOI: 10.1007/s43440-021-00322-3
Abstract: Background Cancer is an ongoing worldwide health problem. Although chemotherapy remains the mainstay therapy for cancer, it is not always effective and has detrimental side effects. Here, we present piperidone compounds P3, P4, and P5… read more here.
Keywords: stress; mediated mechanisms; via protein; cells via ... See more keywords
Immune-Mediated Mechanisms of COVID-19 Neuropathology
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.882905
Abstract: Although SARS-CoV-2 causes a respiratory viral infection, there is a large incidence of neurological complications occurring in COVID-19 patients. These range from headaches and loss of smell to encephalitis and strokes. Little is known about… read more here.
Keywords: mechanisms covid; covid neuropathology; immune mediated; mediated mechanisms ... See more keywords
New Insights into Immune-Mediated Mechanisms in Parkinson’s Disease
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DOI: 10.3390/ijms21239302
Abstract: The immune system has been increasingly recognized as a major contributor in the pathogenesis of Parkinson’s disease (PD). The double-edged nature of the immune system poses a problem in harnessing immunomodulatory therapies to prevent and… read more here.
Keywords: immune; insights immune; immune mediated; parkinson disease ... See more keywords