NF-κB-Mediated Neuroinflammation in Parkinson’s Disease and Potential Therapeutic Effect of Polyphenols
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicity Research"
DOI: 10.1007/s12640-019-00147-2
Abstract: Different animal and human studies from last two decades in the case of Parkinson’s disease (PD) have concentrated on oxidative stress due to increased inflammation and cytokine-dependent neurotoxicity leading to induction of dopaminergic (DA) degeneration… read more here.
Keywords: neuroinflammation; mediated neuroinflammation; parkinson disease; neuroinflammation parkinson ... See more keywords
Icariin targets Nrf2 signaling to inhibit microglia-mediated neuroinflammation.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.05.033
Abstract: Microglia-mediated neuroinflammation is an important contributor to the pathogenesis of neurodegenerative diseases. Inhibition of neuroinflammation has been proved to be effective in neurodegenerative diseases treatment. Nuclear factor erythroid 2 related factor 2 (Nrf2) is a… read more here.
Keywords: microglia mediated; neuroinflammation; mediated neuroinflammation; neurodegenerative diseases ... See more keywords
Xiao-Xu-Ming decoction prevented hemorrhagic transformation induced by acute hyperglycemia through inhibiting AGE-RAGE-mediated neuroinflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological research"
DOI: 10.1016/j.phrs.2021.105650
Abstract: Stroke is one of the leading causes of death worldwide. Hemorrhagic transformation (HT) is a common serious complication of ischemic stroke (IS) and is related to poor prognosis. Hyperglycemia after stroke is associated with the… read more here.
Keywords: rage mediated; mediated neuroinflammation; age rage; hyperglycemia ... See more keywords
Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s350109
Abstract: Abstract Microglia are tissue-resident macrophages of the central nervous system (CNS). In the CNS, microglia play an important role in the monitoring and intervention of synaptic and neuron-level activities. Interventions targeting microglia have been shown… read more here.
Keywords: mediated neuroinflammation; cardiovascular diseases; neuroinflammation potential; microglia mediated ... See more keywords
Galectin-3 in Microglia-Mediated Neuroinflammation: Implications for Central Nervous System Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Current Neuropharmacology"
DOI: 10.2174/1570159x20666220201094547
Abstract: Microglial activation is one of the common hallmarks shared by various central nervous system (CNS) diseases. Based on surrounding circumstances, activated microglia play either detrimental or neuroprotective effects. Galectin-3 (Gal-3), a group of β-galactoside-binding proteins,… read more here.
Keywords: mediated neuroinflammation; cns diseases; neuroinflammation; central nervous ... See more keywords
Microglia-mediated neuroinflammation and neuroplasticity after stroke
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.980722
Abstract: Stroke remains a major cause of long-term disability and mortality worldwide. The immune system plays an important role in determining the condition of the brain following stroke. As the resident innate immune cells of the… read more here.
Keywords: mediated neuroinflammation; microglia mediated; brain; neuroinflammation neuroplasticity ... See more keywords
Multi-Target Effects of ß-Caryophyllene and Carnosic Acid at the Crossroads of Mitochondrial Dysfunction and Neurodegeneration: From Oxidative Stress to Microglia-Mediated Neuroinflammation
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11061199
Abstract: Inflammation and oxidative stress are interlinked and interdependent processes involved in many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases, and cancer. Therefore, targeting inflammatory pathways may represent a potential therapeutic strategy. Emerging evidence indicates that… read more here.
Keywords: mediated neuroinflammation; oxidative stress; mitochondrial dysfunction; neurodegeneration ... See more keywords
Nicotinamide Ameliorates Amyloid Beta-Induced Oxidative Stress-Mediated Neuroinflammation and Neurodegeneration in Adult Mouse Brain
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9040408
Abstract: Alzheimer’s disease (AD) is the most predominant age-related neurodegenerative disease, pathologically characterized by the accumulation of aggregates of amyloid beta Aβ1–42 and tau hyperphosphorylation in the brain. It is considered to be the primary cause… read more here.
Keywords: amyloid beta; mediated neuroinflammation; neurodegeneration; neuroinflammation neurodegeneration ... See more keywords
Targeting NLRP3-Mediated Neuroinflammation in Alzheimer’s Disease Treatment
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23168979
Abstract: Alzheimer’s disease (AD) is the most common cause of dementia in the general population and, to date, constitutes a major therapeutic challenge. In the pathogenesis of AD, aggregates of amyloid β (Aβ) and neurofibrillary tangles… read more here.
Keywords: mediated neuroinflammation; alzheimer disease; pathology; targeting nlrp3 ... See more keywords
Glial Cell-Mediated Neuroinflammation in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810572
Abstract: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder; it is the most common cause of dementia and has no treatment. It is characterized by two pathological hallmarks, the extracellular deposits of amyloid beta (Aβ) and… read more here.
Keywords: mediated neuroinflammation; neuroinflammation; disease; alzheimer disease ... See more keywords