Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D
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DOI: 10.1021/acschemneuro.2c00208
Abstract: Neuroprotective properties of five previously described furanoditerpenes 1–5, isolated from Spongia (Spongia) tubulifera, were evaluated in an in vitro oxidative stress model in SH-SY5Y cells. Dose–response treatments revealed that 1–5 improved cell survival at nanomolar… read more here.
Keywords: spongia spongia; mitochondrial mediated; mediated neuroprotective; cyclophilin ... See more keywords