Protective effect of Sulforaphane against Arsenic-induced hepatotoxicity in rats: Role of PI3K/Akt-mediated Nrf2 signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.295
Abstract: Background Industrial and agricultural growths in recent years has resulted in the extreme discharge of arsenic into the environment, making arsenic toxicity a major worldwide concern. Oxidative stress is considered the primary mechanism for arsenic… read more here.
Keywords: mediated nrf2; akt; pi3k akt; arsenic induced ... See more keywords
Melanocyte‐protective effect of afzelin is mediated by the Nrf2‐ARE signalling pathway via GSK‐3β inactivation
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Dermatology"
DOI: 10.1111/exd.13277
Abstract: Vitiligo is an acquired condition characterized by depigmented, cutaneous lesions that result from the death of pigment‐producing cells, melanocytes. The occurrence of oxidative stress has been proposed as a pathogenetic mechanism for melanocyte degeneration in… read more here.
Keywords: mediated nrf2; via gsk; effect afzelin; afzelin ... See more keywords
Protective effect of dexmedetomidine against delayed bone healing caused by morphine via PI3K/Akt mediated Nrf2 antioxidant defense system
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2024.1396713
Abstract: Background As a class of analgesics, opioids are frequently used to treat both acute and chronic moderate to severe pain. Patients frequently receive opioid painkillers after orthopedic accidents or surgeries. Evidence suggests that opioid drug… read more here.
Keywords: bone healing; dex; dexmedetomidine; bone ... See more keywords