A Synthesis Strategy for the Production of a Macrolactone of Gulmirecin A via a Ni(0)-Mediated Reductive Cyclization Reaction.
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DOI: 10.1021/acs.orglett.0c00665
Abstract: A synthesis strategy for the production of a key synthetic intermediate of gulmirecin A was described. The key reaction in the preparation of the 12-membered macrolactone is the Ni(0)-mediated reductive cyclization reaction of ynal using… read more here.
Keywords: synthesis strategy; reductive cyclization; reaction; gulmirecin ... See more keywords
Thiolate-mediated Reductive Cyclizations: Scope, Limitation and Novel Mechanistic Insights
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DOI: 10.1246/cl.200411
Abstract: Substrate scope of the thiolate-mediated reductive cyclization of keto-enones was studied, revealing the applicability and novel mechanistic insights. read more here.
Keywords: reductive cyclizations; novel mechanistic; mediated reductive; mechanistic insights ... See more keywords