Capturing the Onset of PRC2-Mediated Repressive Domain Formation.
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DOI: 10.1016/j.molcel.2018.05.023
Abstract: Polycomb repressive complex 2 (PRC2) maintains gene silencing by catalyzing methylation of histone H3 at lysine 27 (H3K27me2/3) within chromatin. By designing a system whereby PRC2-mediated repressive domains were collapsed and then reconstructed in an… read more here.
Keywords: domain formation; mediated repressive; h3k27me2; prc2 ... See more keywords