TALE-triggered and iTALE-suppressed Xa1-mediated resistance to bacterial blight is independent of rice transcription factor subunits OsTFIIAγ1 or OsTFIIAγ5.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of experimental botany"
DOI: 10.1093/jxb/erab054
Abstract: Xa1-mediated resistance to rice bacterial blight, caused by Xanthomonas oryzae pv. oryzae (Xoo), is triggered by transcription activator-like effectors (TALEs) and suppressed by interfering TALEs (iTALEs). TALEs interact with the rice transcription factor OsTFIIAγ1 or… read more here.
Keywords: xa1 mediated; mediated resistance; ostfiia ostfiia; rice ... See more keywords
The multiple combination of Paclitaxel, Ramucirumab and Elacridar reverses the paclitaxel-mediated resistance in gastric cancer cell lines
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1129832
Abstract: Introduction Paclitaxel (PTX) interferes with microtubule architecture by binding to β-tubulin, thereby blocking progression at the G2/M phase and inducing apoptosis. This study aimed to investigate molecular processes underlying PTX-mediated resistance in gastric cancer (GC)… read more here.
Keywords: mediated resistance; ptx; ramucirumab; elacridar ... See more keywords
Blocked at the Stomatal Gate, a Key Step of Wheat Stb16q-Mediated Resistance to Zymoseptoria tritici
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.921074
Abstract: Septoria tritici blotch (STB), caused by the fungus Zymoseptoria tritici, is among the most threatening wheat diseases in Europe. Genetic resistance remains one of the main environmentally sustainable strategies to efficiently control STB. However, the… read more here.
Keywords: mediated resistance; wheat; tritici; stb16q mediated ... See more keywords
What Approaches to Thwart Bacterial Efflux Pumps-Mediated Resistance?
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DOI: 10.3390/antibiotics11101287
Abstract: An effective response that combines prevention and treatment is still the most anticipated solution to the increasing incidence of antimicrobial resistance (AMR). As the phenomenon continues to evolve, AMR is driving an escalation of hard-to-treat… read more here.
Keywords: efflux pumps; thwart bacterial; mediated resistance; approaches thwart ... See more keywords
CRISPR/Cas-Mediated Resistance against Viruses in Plants
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DOI: 10.3390/ijms23042303
Abstract: CRISPR/Cas9 provides a robust and widely adaptable system with enormous potential for genome editing directed towards generating useful products. It has been used extensively to generate resistance against viruses infecting plants with more effective and… read more here.
Keywords: mediated resistance; resistance; resistance viruses; cas mediated ... See more keywords
Inhibition of Enzymatic Acetylation-Mediated Resistance to Plazomicin by Silver Ions
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DOI: 10.3390/ph16020236
Abstract: Plazomicin is a recent U.S. Food and Drug Administration (FDA)-approved semisynthetic aminoglycoside. Its structure consists of a sisomicin scaffold modified by adding a 2(S)-hydroxy aminobutyryl group at the N1 position and a hydroxyethyl substituent at… read more here.
Keywords: acetylation; mediated resistance; silver; plazomicin ... See more keywords
RNAi-Mediated Resistance Against Viruses in Perennial Fruit Plants
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DOI: 10.3390/plants8100359
Abstract: Small RNAs (sRNAs) are 20–30-nucleotide-long, regulatory, noncoding RNAs that induce silencing of target genes at the transcriptional and posttranscriptional levels. They are key components for cellular functions during plant development, hormone signaling, and stress responses.… read more here.
Keywords: mediated resistance; plant; plants rnai; resistance viruses ... See more keywords