The HLA-DR mediated signalling increases the migration and invasion of melanoma cells, the expression and lipid raft recruitment of adhesion receptors, PD-L1 and signal transduction proteins.
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DOI: 10.1016/j.cellsig.2017.05.008
Abstract: The constitutive expression of Major Histocompatibility Complex (MHC) class II molecules is restricted to professional Antigen-Presenting Cells (APCs), nevertheless almost 50% of melanomas express constitutively the MHC class II molecules. Therefore, in two MHC class… read more here.
Keywords: mediated signalling; melanoma; class; hla mediated ... See more keywords
Contribution of CARD9‐mediated signalling to wound healing in skin
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DOI: 10.1111/exd.13389
Abstract: The inflammatory response after skin injury involves the secretion of a variety of cytokines and growth factors that are necessary for tissue repair. Caspase recruitment domain‐containing protein 9 (CARD9) is an essential signalling adaptor molecule… read more here.
Keywords: mediated signalling; wound healing; card9; card9 mediated ... See more keywords