Nanoparticle-Mediated In Situ Molecular Reprogramming of Immune Checkpoint Interactions for Cancer Immunotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "ACS nano"
DOI: 10.1021/acsnano.1c04456
Abstract: Immune checkpoint blockade involves targeting immune regulatory molecules with antibodies. Preclinically, complex multiantibody regimes of both inhibitory and stimulatory targets are a promising candidate for the next generation of immunotherapy. However, in this setting, the… read more here.
Keywords: immune checkpoint; immunotherapy; mediated situ; checkpoint interactions ... See more keywords
Bacteria-mediated in situ polymerization of peptide-modified acrylamide for enhancing antimicrobial activity.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03858g
Abstract: Bacteria-mediated reactions can utilize the natural activities of bacteria to produce bioactive products. Here, bacteria-mediated polymerization of the acrylamide-functionalized peptide Trp-Arg-Lys (Am-WRK) afforded an antibacterial polymer, PAm-WRK, which simulates the cationic and hydrophobic structures of… read more here.
Keywords: polymerization peptide; situ polymerization; mediated situ; bacteria mediated ... See more keywords