Structure of polymerized type V pilin reveals assembly mechanism involving protease-mediated strand exchange
Sign Up to like & getrecommendations! Published in 2020 at "Nature Microbiology"
DOI: 10.1038/s41564-020-0705-1
Abstract: Bacterial adhesion is a general strategy for host–microbe and microbe–microbe interactions. Adhesive pili are essential for colonization, biofilm formation, virulence and pathogenesis of many environmental and pathogenic bacteria 1 , 2 . Members of the… read more here.
Keywords: protease mediated; protease; assembly mechanism; mediated strand ... See more keywords
Photocontrolled dissociation and toehold-mediated strand displacement-based synergistic regulation of CRISPR-Cas12a
Sign Up to like & getrecommendations! Published in 2025 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaf1178
Abstract: Abstract The trans-cleavage activity of the CRISPR-Cas system holds broad potential across diverse fields, yet precise spatiotemporal regulation remains challenging due to the predominantly single-direction control strategies available. Here, we present a bidirectional, multi-round modulation… read more here.
Keywords: toehold mediated; strand displacement; crispr cas12a; mediated strand ... See more keywords