Arsenic trioxide-mediated suppression of miR-182-5p is associated with potent anti-oxidant effects through up-regulation of SESN2
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DOI: 10.18632/oncotarget.24678
Abstract: Arsenic trioxide (ATO) is a traditional Chinese medicine that can induce oxidative stress for treatment of cancer cells. However, ATO may generate anti-oxidative responses to compromise the cytotoxic effect, but the underlying mechanisms remain unclear.… read more here.
Keywords: anti oxidant; mir; mir 182; suppression mir ... See more keywords
Involvement of MAFB and MAFF in Retinoid-Mediated Suppression of Hepatocellular Carcinoma Invasion
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DOI: 10.3390/ijms19051450
Abstract: Retinoids exert antitumor effects through the retinoic acid receptor α (RARα). In the present study, we sought to identify the factors involved in the RARα-mediated transcriptional regulation of the tumor suppressor gene and the tissue… read more here.
Keywords: hepatocellular carcinoma; maff; invasion; mediated suppression ... See more keywords