Sulphotransferase-mediated toxification of chemicals in mouse models: effect of knockout or humanisation of SULT genes
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DOI: 10.1042/ebc20240030
Abstract: Abstract Cytosolic sulphotransferase (SULT) enzymes catalyse reactions involved in xenobiotic elimination and hormone regulation. However, SULTs can also generate electrophilic reactive intermediates from certain substrates, including the activation of carcinogens. Here, we review toxicological studies… read more here.
Keywords: toxification chemicals; mediated toxification; sulphotransferase mediated; sulphotransferase ... See more keywords