NSP-C contributes to the upregulation of CLOCK/BMAL1-mediated transcription
Sign Up to like & getrecommendations! Published in 2018 at "Cytotechnology"
DOI: 10.1007/s10616-018-0266-9
Abstract: The bHLH-PAS transcription factors clock circadian regulator (CLOCK) and brain and muscle ARNT-like protein 1 (BMAL1) play essential roles in the generation of circadian gene expression rhythms through the activation of E-box-mediated transcription. Importantly, circadian… read more here.
Keywords: bmal1; clock bmal1; bmal1 mediated; clock ... See more keywords
Advancements in chemical biology targeting the kinases and phosphatases of RNA polymerase II-mediated transcription.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2021.02.002
Abstract: Phosphorylation of RNA polymerase II (RNAP II) coordinates the temporal progression of eukaryotic transcription. The development and application of chemical genetic methods have enhanced our ability to investigate the intricate and intertwined pathways regulated by… read more here.
Keywords: kinases phosphatases; transcription; chemical biology; rna polymerase ... See more keywords
Catalase ameliorates diabetes‐induced cardiac injury through reduced p65/RelA‐ mediated transcription of BECN1
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13252
Abstract: Catalase is an antioxidative enzyme that converts hydrogen peroxide (H2O2) produced by superoxide dismutase from highly reactive superoxide (O2−) to water and oxygen molecules. Although recent findings demonstrate that catalase, autophagy and the nuclear factor… read more here.
Keywords: catalase ameliorates; ameliorates diabetes; transcription becn1; catalase ... See more keywords
Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.817526
Abstract: Psoriasis is a chronic and inflammatory skin disorder characterized by inflammation and epidermal hyperplasia. Punicalagin (PUN) is a main active ingredient of pomegranate (Punica granatum L.) peel with multiple biological activities, such as antibacterial, antioxidant… read more here.
Keywords: regulated secretion; transcription caspase; punicalagin; psoriasis ... See more keywords