RAF Binding Preferences Dictate RAS-Mediated Tumorigenesis.
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DOI: 10.1158/2159-8290.cd-rw2019-158
Abstract: Distinct binding between RAS and RAF family members determines RAS signaling. read more here.
Keywords: mediated tumorigenesis; binding preferences; raf binding; preferences dictate ... See more keywords
Asparaginyl-tRNA Synthetase, a Novel Component of Hippo Signaling, Binds to Salvador and Enhances Yorkie-Mediated Tumorigenesis
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DOI: 10.3389/fcell.2020.00032
Abstract: Aminoacyl-tRNA synthetases (ARSs), which are essential for protein translation, were recently shown to have non-translational functions in various pathological conditions including cancer. However, the molecular mechanism underlying the role of ARSs in cancer remains unknown.… read more here.
Keywords: hippo; asparaginyl trna; mediated tumorigenesis; hippo signaling ... See more keywords
Integrin-Mediated Tumorigenesis and Its Therapeutic Applications
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DOI: 10.3389/fonc.2022.812480
Abstract: Integrins, a family of adhesion molecules generally exist on the cell surface, are essential for regulating cell growth and its function. As a bi-directional signaling molecule, they mediate cell-cell and cell-extracellular matrix interaction. The recognitions… read more here.
Keywords: mediated tumorigenesis; therapeutic applications; cell; tumorigenesis therapeutic ... See more keywords