Sphingosine kinase 1 mediates AGEs-induced fibronectin upregulation in diabetic nephropathy
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DOI: 10.18632/oncotarget.20205
Abstract: Activation of sphingosine kinase 1 (SphK1) signaling pathway mediates fibronectin (FN) upregulation in glomerular mesangial cells (GMCs) under high glucose (HG) condition. However, the roles of SphK1 in advanced glycation end products (AGEs)-induced DN have… read more here.
Keywords: fibronectin upregulation; sphingosine kinase; ages induced; sphk1 ... See more keywords