IL-2 mediates NK cell proliferation but not hyperactivity
Sign Up to like & getrecommendations! Published in 2018 at "Immunologic Research"
DOI: 10.1007/s12026-017-8982-3
Abstract: Natural killer cells play a major role in innate immunity against tumor and virus-infected cells. NK cells express activating and inhibitory receptors to regulate their function. It has been established that modulation in the NK… read more here.
Keywords: cell proliferation; stimulation; proliferation hyperactivity; mediates cell ... See more keywords
Primary cilium remodeling mediates a cell signaling switch in differentiating neurons
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DOI: 10.1126/sciadv.abb0601
Abstract: Newborn neurons assemble a new primary cilium, leading to a change in the mode of Shh signaling that now directs axon extension. Cellular differentiation leads to the formation of specialized cell types and complex morphological… read more here.
Keywords: cilium; differentiating neurons; mediates cell; cilium remodeling ... See more keywords
Transcription Factor AP4 Mediates Cell Fate Decisions: To Divide, Age, or Die
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13040676
Abstract: Simple Summary Here, we review the literature on Activating Enhancer-Binding Protein 4 (AP4)/transcription factor AP4 (TFAP4) function and regulation and its role in cancer. Elevated expression of AP4 was detected in tumors of various organs… read more here.
Keywords: ap4; transcription factor; factor ap4; mediates cell ... See more keywords