Articles with "mediates metabolic" as a keyword



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GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK.

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Published in 2021 at "Cell reports"

DOI: 10.1016/j.celrep.2021.109501

Abstract: Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) activates AMP-activated protein kinase (AMPK) and plays a crucial role in glucose and lipid metabolism. Here, we examine whether PPARβ/δ activation effects depend on growth differentiation factor 15 (GDF15), a… read more here.

Keywords: effects ppar; gdf15; ampk; activation ... See more keywords