Articles with "mediates microglial" as a keyword



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TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function

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Published in 2018 at "Neuron"

DOI: 10.1016/j.neuron.2018.01.031

Abstract: Mutations in triggering receptor expressed on myeloid cells 2 (TREM2) have been linked to increased Alzheimer's disease (AD) risk. Neurobiological functions of TREM2 and its pathophysiological ligands remain elusive. Here we found that TREM2 directly… read more here.

Keywords: microglial function; mediates microglial; amyloid mediates; receptor amyloid ... See more keywords