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Tau Mediates Synergistic Influence of Vascular Risk and Aβ on Cognitive Decline

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Published in 2022 at "Annals of Neurology"

DOI: 10.1002/ana.26460

Abstract: Elevated vascular risk and beta‐amyloid (Aβ) burden have been synergistically associated with cognitive decline in preclinical Alzheimer's disease (AD), although the underlying mechanisms remain unclear. We examined whether accelerated longitudinal tau accumulation mediates the vascular… read more here.

Keywords: mediates synergistic; tau mediates; vascular risk; cognitive decline ... See more keywords