Articles with "mediating protein" as a keyword



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RPB5‐Mediating Protein Promotes Cholangiocarcinoma Tumorigenesis and Drug Resistance by Competing With NRF2 for KEAP1 Binding

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Published in 2019 at "Hepatology"

DOI: 10.1002/hep.30962

Abstract: Cancer cell survival depends on the balance between reactive oxygen species production and scavenging, which is regulated primarily by NRF2 during tumorigenesis. Here, we demonstrate that deletion of RBP5‐mediating protein (RMP) in an autonomous mouse… read more here.

Keywords: mediating protein; tumorigenesis; rpb5 mediating; promotes cholangiocarcinoma ... See more keywords