Nuisance mediators and missing data in mediation analyses of pain trials
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DOI: 10.1002/ejp.1637
Abstract: This journal recently published a paper by O'Neill and colleagues, entitled "Examining what factors mediate treatment effect in chronic low back pain: a mediation analysis of a Cognitive Functional Therapy clinical trial” (O’Neill, O’Sullivan, O’Sullivan,… read more here.
Keywords: data mediation; mediators missing; nuisance mediators; mediation ... See more keywords
Causal mediation analysis with multiple causally non-ordered mediators
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DOI: 10.1177/0962280215615899
Abstract: In many health studies, researchers are interested in estimating the treatment effects on the outcome around and through an intermediate variable. Such causal mediation analyses aim to understand the mechanisms that explain the treatment effect.… read more here.
Keywords: non ordered; causal mediation; mediation; causally non ... See more keywords
Incorporating nonlinearity into mediation analyses
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DOI: 10.1186/s12874-017-0296-6
Abstract: BackgroundMediation is an important issue considered in the behavioral, medical, and social sciences. It addresses situations where the effect of a predictor variable X on an outcome variable Y is explained to some extent by… read more here.
Keywords: nonlinearity mediation; incorporating nonlinearity; mediation; mediation analyses ... See more keywords
Mediation Analyses of the Role of Apathy on Motoric Cognitive Outcomes
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DOI: 10.3390/ijerph19127376
Abstract: Recent literature indicates that apathy is associated with poor cognitive and functional outcomes in older adults, including motoric cognitive risk syndrome (MCR), a predementia syndrome. However, the underlying biological pathway is unknown. The objectives of… read more here.
Keywords: mediation analyses; cognitive outcomes; role; motoric cognitive ... See more keywords