Hereditary alpha tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis.
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DOI: 10.1182/blood.2020006157
Abstract: Mastocytosis is a hematopoietic neoplasm characterized by expansion of KIT D816V-mutated clonal mast cells in various organs and severe or even life-threatening anaphylactic reactions. Recently, hereditary α-tryptasemia (HαT) has been described as a common genetic… read more here.
Keywords: tryptase; mediator related; tryptasemia; related symptoms ... See more keywords