Social and medical need for whole genome high resolution NIPT
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1062
Abstract: Two technological innovations in the last decade significantly influenced the diagnostic yield of prenatal cytogenetic testing: genomic microarray allowing high resolution analysis and noninvasive prenatal testing (NIPT) focusing on aneuploidy. To anticipate future trends in… read more here.
Keywords: medical need; resolution; high resolution; whole genome ... See more keywords
Primary osteoporosis in men: an unmet medical need.
Sign Up to like & getrecommendations! Published in 2019 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2019.10.003
Abstract: Osteoporosis is a skeletal disease characterized by loss of bone strength and increased risk of fractures. Even though fracture prevalence is higher in women, fractures also constitute a significant public health issue in older men.… read more here.
Keywords: medical need; primary osteoporosis; unmet medical; men unmet ... See more keywords
Emerging pharmaceutical therapies for osteoarthritis
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-020-00518-6
Abstract: The prevalence of osteoarthritis (OA) and the burden associated with the disease are steadily increasing worldwide, representing a major public health challenge for the coming decades. The lack of specific treatments for OA has led… read more here.
Keywords: medical need; unmet medical; disease; pharmaceutical therapies ... See more keywords
The Growing Medical Need for Tracheal Replacement: Reconstructive Strategies Should Overcome Their Limits
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.846632
Abstract: Breathing, being predominantly an automatic action, is often taken for granted. However, respiratory diseases affect millions of people globally, emerging as one of the major causes of disability and death overall. Among the respiratory dysfunctions,… read more here.
Keywords: replacement reconstructive; need tracheal; medical need; growing medical ... See more keywords
Overview on Therapeutic Options in Uncommon EGFR Mutant Non-Small Cell Lung Cancer (NSCLC): New Lights for an Unmet Medical Need
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108878
Abstract: The majority of epidermal growth factor receptor (EGFR) mutations (85–90%) are exon 19 deletions and L858R point mutations of exon 21, characterized by high sensitivity to EGFR-tyrosine kinase inhibitors (TKIs). Less is known about uncommon… read more here.
Keywords: lung cancer; medical need; unmet medical; egfr mutations ... See more keywords