Assessment of Limitations to Optimization of Guideline-Directed Medical Therapy in Heart Failure From the GUIDE-IT Trial: A Secondary Analysis of a Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2020.0640
Abstract: Importance Despite evidence that guideline-directed medical therapy (GDMT) improves outcomes in patients with heart failure (HF) and reduced ejection fraction, many patients are undertreated. The Guiding Evidence-Based Therapy Using Biomarker Intensified Treatment (GUIDE-IT) trial tested… read more here.
Keywords: trial; guideline directed; analysis; medical therapy ... See more keywords
Initial Thoracic Endovascular Aortic Repair vs Medical Therapy for Acute Uncomplicated Type B Aortic Dissection.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.4187
Abstract: Importance Thoracic endovascular aortic repair (TEVAR) has increasingly been used for uncomplicated type B aortic dissection (uTBAD) despite limited supporting data. Objective To assess whether initial TEVAR following uTBAD is associated with reduced mortality or… read more here.
Keywords: tevar; mortality; medical therapy; initial tevar ... See more keywords
Estimated Cost-effectiveness of Medical Therapy, Sleeve Gastrectomy, and Gastric Bypass in Patients With Severe Obesity and Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.48317
Abstract: Key Points Question Compared with medical therapy, is bariatric surgery with sleeve gastrectomy or Roux-en-Y gastric bypass (RYGB) associated with cost-effective weight reduction in patients with severe obesity and varying type 2 diabetes (T2D) severity?… read more here.
Keywords: cost; patients severe; severe obesity; sleeve gastrectomy ... See more keywords
Optimal medical therapy vs. coronary revascularization for patients presenting with chronic total occlusion: A meta‐analysis of randomized controlled trials and propensity score adjusted studies
Sign Up to like & getrecommendations! Published in 2019 at "Catheterization and Cardiovascular Interventions"
DOI: 10.1002/ccd.28037
Abstract: The optimal management of patients with coronary chronic total occlusions (CTO) remains controversial. This meta‐analysis aims to compare percutaneous coronary intervention of CTO (CTO‐PCI) versus optimal medical therapy (OMT) in CTO patients. read more here.
Keywords: optimal medical; medical therapy; chronic total; meta analysis ... See more keywords
Impact of revascularization versus medical therapy alone for chronic total occlusion management in older patients
Sign Up to like & getrecommendations! Published in 2019 at "Catheterization and Cardiovascular Interventions"
DOI: 10.1002/ccd.28163
Abstract: Chronic total occlusions (CTOs) are present in more than one third of older patients with myocardial ischemia, but controversy remains about the best therapeutic approach. read more here.
Keywords: versus medical; impact revascularization; medical therapy; revascularization versus ... See more keywords
Frailty interferes with the guideline‐directed medical therapy in heart failure patients with reduced ejection fraction
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14163
Abstract: Guideline‐directed medical therapy (GDMT) in patients with heart failure with reduced ejection fraction (HFrEF) is recommended in clinical guidelines, but elderly patients have not fully received GDMT in the clinical situation. The aim of this… read more here.
Keywords: heart failure; directed medical; guideline directed; heart ... See more keywords
Individualizing surgical revascularization in patients with ischaemic heart failure — a further dive into STICHES
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.1426
Abstract: In the Surgical Treatment for Ischemic Heart Failure (STICH) trial, 1212 patients with heart failure and reduced ejection fraction (HFrEF) and significant coronary artery disease were randomized to coronary artery bypass grafting (CABG) plus medical… read more here.
Keywords: heart; morbidity; medical therapy; heart failure ... See more keywords
Clinical inertia and medical therapy for heart failure: the unintended harms of ‘first, do no harm’
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2283
Abstract: Conceptually embodied within the Hippocratic Oath, this phrase is taught to students in healthcare across the world as one of the core principles of medical ethics and clinician responsibility. In part, the phrase is meant… read more here.
Keywords: therapy; first harm; medical therapy; heart failure ... See more keywords
Clinical implications of left atrial changes after optimization of medical therapy in patients with heart failure
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2593
Abstract: Limited data exist regarding the prognostic relevance of changes in left atrial (LA) dimensions in patients with heart failure (HF). We assessed changes in LA dimension and their relation with outcomes after optimization of guideline‐directed… read more here.
Keywords: heart failure; patients heart; heart; left atrial ... See more keywords
March 2023 at a glance: pathophysiology, medical therapy and devices
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2834
Abstract: Interatrial shunt (IAS) devices are emerging as a novel treatment option for patients with heart failure (HF) and mildly reduced or preserved ejection fraction (HFpEF).1–3 Latent pulmonary vascular disease might affect the benefits of IAS… read more here.
Keywords: 2023 glance; pathophysiology medical; glance pathophysiology; pulmonary vascular ... See more keywords
The impact of medical therapy on left ventricular strain: Current state and future perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Ultrasound"
DOI: 10.1002/jcu.23244
Abstract: The speckle tracking strain is becoming a frequently used marker of subclinical left ventricular systolic dysfunction. Despite the wide range of data concerning left ventricular strain variability in the general population and its changes in… read more here.
Keywords: therapy left; ventricular strain; strain; impact medical ... See more keywords