Medicinal Applications of Gold(I/III)-Based Complexes Bearing N-Heterocyclic Carbene and Phosphine Ligands
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2018.04.023
Abstract: Abstract Phosphines are the most studied ligands on gold-based metallodrugs, whereas N-heterocyclic carbenes (NHCs) have been emerging in the past years as potential alternative ligands for medicinal applications. Indeed, in both cases, phosphine and NHC… read more here.
Keywords: ligands medicinal; iii; applications gold; phosphine ... See more keywords
Cyclodextrin-based rotaxanes as a versatile platform for biological and medicinal applications
Sign Up to like & getrecommendations! Published in 2025 at "Communications Chemistry"
DOI: 10.1038/s42004-025-01555-6
Abstract: Mechanically interlocked molecules (MIMs) such as rotaxanes and catenanes attract significant interest due to their unique structures and dynamic properties. Cyclodextrin-based rotaxanes (CD-rotaxanes) have emerged as promising supramolecular systems for biological and medicinal applications. Their… read more here.
Keywords: cyclodextrin based; based rotaxanes; medicinal applications; rotaxanes versatile ... See more keywords
Recent Synthetic Advancement and Medicinal Applications of Asymmetric Cyclic Pyrazoline-based Hydrazine Derivatives: A Review.
Sign Up to like & getrecommendations! Published in 2025 at "Current topics in medicinal chemistry"
DOI: 10.2174/0115680266374814250422053723
Abstract: Chemistry research focuses on reducing energy and minimizing harmful byproducts. Pyrazoline and its derivatives have various pharmacological properties. This study aims to compile procedures for creating pyrazoline scaffolds from academic articles and online resources, such… read more here.
Keywords: chemistry; synthetic advancement; recent synthetic; medicinal applications ... See more keywords
N-Heterocyclic Carbene-Silver(I) Complexes: Emerging Developments for Medicinal Applications
Sign Up to like & getrecommendations! Published in 2025 at "Current Bioactive Compounds"
DOI: 10.2174/0115734072349038250131050619
Abstract: The increased applications of silver(I)-NHC complexes have led researchers to explore their medicinal studies and chemical properties. Silver(I) ions have proven to be considerable antimicrobial and anticancer agents, and their incorporation into various medical and… read more here.
Keywords: carbene silver; nhc complexes; silver nhc; heterocyclic carbene ... See more keywords
Biosensors in Diagnostics and Medicinal Applications Part (II).
Sign Up to like & getrecommendations! Published in 2024 at "Current topics in medicinal chemistry"
DOI: 10.2174/156802662411240506092520
Abstract: read more here.
Keywords: diagnostics medicinal; chemistry; applications part; biosensors diagnostics ... See more keywords
Advances in Synthesis and Medicinal Applications of Compounds Derived from Phthalimide.
Sign Up to like & getrecommendations! Published in 2020 at "Current organic synthesis"
DOI: 10.2174/1570179417666200325124712
Abstract: Phthalimide derivatives have been presenting several promising biological activities in the literature, such as anti-inflammatory and analgesic, antitumor, antimicrobial, anticonvulsant, among others. The most well known and studied phthalimide derivative (isoindoline-1,3-dione) is thalidomide, because this… read more here.
Keywords: synthesis medicinal; advances synthesis; medicinal applications; applications compounds ... See more keywords
Antioxidant Activities of Natural Polysaccharides and Their Derivatives for Biomedical and Medicinal Applications
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11122491
Abstract: Many chronic diseases such as Alzheimer’s disease, diabetes, and cardiovascular diseases are closely related to in vivo oxidative stress caused by excessive reactive oxygen species (ROS). Natural polysaccharides, as a kind of biomacromolecule with good… read more here.
Keywords: natural polysaccharides; biomedical medicinal; antioxidant activities; medicinal applications ... See more keywords
Indole-Containing Metal Complexes and Their Medicinal Applications
Sign Up to like & getrecommendations! Published in 2024 at "Molecules"
DOI: 10.3390/molecules29020484
Abstract: Indole is an important element of many natural and synthetic molecules with significant biological activity. Nonetheless, the co-presence of transitional metals in organic scaffold may represent an important factor in the development of effective medicinal… read more here.
Keywords: containing metal; indole containing; medicinal applications; complexes medicinal ... See more keywords
Recent Advances in the Development of Metal-Glycoconjugates for Medicinal Applications
Sign Up to like & getrecommendations! Published in 2025 at "Molecules"
DOI: 10.3390/molecules30173537
Abstract: Rapidly proliferating tumor cells exhibit elevated demands for nutrients and energy to support their uncontrolled growth, with glucose serving as a key metabolic substrate. Glucose is transported into cells via facilitated diffusion mediated by glucose… read more here.
Keywords: glycoconjugates medicinal; medicinal applications; metal; tumor ... See more keywords
Recent advances in thymidine phosphorylase inhibitors: syntheses and prospective medicinal applications
Sign Up to like & getrecommendations! Published in 2017 at "Turkish Journal of Chemistry"
DOI: 10.3906/kim-1602-79
Abstract: This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades. A brief introduction covering the structural aspects of TPase inhibitors is… read more here.
Keywords: thymidine phosphorylase; advances thymidine; medicinal applications; inhibitors syntheses ... See more keywords