Medicinal Applications of Gold(I/III)-Based Complexes Bearing N-Heterocyclic Carbene and Phosphine Ligands
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2018.04.023
Abstract: Abstract Phosphines are the most studied ligands on gold-based metallodrugs, whereas N-heterocyclic carbenes (NHCs) have been emerging in the past years as potential alternative ligands for medicinal applications. Indeed, in both cases, phosphine and NHC… read more here.
Keywords: ligands medicinal; iii; applications gold; phosphine ... See more keywords
Advances in Synthesis and Medicinal Applications of Compounds Derived from Phthalimide.
Sign Up to like & getrecommendations! Published in 2020 at "Current organic synthesis"
DOI: 10.2174/1570179417666200325124712
Abstract: Phthalimide derivatives have been presenting several promising biological activities in the literature, such as anti-inflammatory and analgesic, antitumor, antimicrobial, anticonvulsant, among others. The most well known and studied phthalimide derivative (isoindoline-1,3-dione) is thalidomide, because this… read more here.
Keywords: synthesis medicinal; advances synthesis; medicinal applications; applications compounds ... See more keywords
Antioxidant Activities of Natural Polysaccharides and Their Derivatives for Biomedical and Medicinal Applications
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11122491
Abstract: Many chronic diseases such as Alzheimer’s disease, diabetes, and cardiovascular diseases are closely related to in vivo oxidative stress caused by excessive reactive oxygen species (ROS). Natural polysaccharides, as a kind of biomacromolecule with good… read more here.
Keywords: natural polysaccharides; biomedical medicinal; antioxidant activities; medicinal applications ... See more keywords
Recent advances in thymidine phosphorylase inhibitors: syntheses and prospective medicinal applications
Sign Up to like & getrecommendations! Published in 2017 at "Turkish Journal of Chemistry"
DOI: 10.3906/kim-1602-79
Abstract: This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades. A brief introduction covering the structural aspects of TPase inhibitors is… read more here.
Keywords: thymidine phosphorylase; advances thymidine; medicinal applications; inhibitors syntheses ... See more keywords