Molecular-decoration technique offers boost to medicinal chemists
Sign Up to like & getrecommendations! Published in 2019 at "Nature"
DOI: 10.1038/d41586-019-00767-w
Abstract: The ability to attach a variety of chemical groups to one position in a molecule facilitates the search for compounds that have useful properties. Reactions have been reported that could transform how chemists do this.Cross-coupling… read more here.
Keywords: offers boost; boost medicinal; decoration technique; medicinal chemists ... See more keywords
Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules28010271
Abstract: Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime. The number of chiral, non-racemic drugs on… read more here.
Keywords: medicinal chemists; organocatalysis survival; survival guide; chemistry ... See more keywords