Application of Novel Degraders Employing Autophagy for Expediting Medicinal Research.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01712
Abstract: Targeted protein degradation (TPD) technology is based on a unique pharmacological mechanism that has profoundly revolutionized medicinal research by overcoming limitations associated with traditional small-molecule drugs. Autophagy, a mechanism for intracellular waste disposal and recovery,… read more here.
Keywords: novel degraders; application novel; medicinal research; degraders employing ... See more keywords
Recent advances of tanshinone in regulating autophagy for medicinal research
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1059360
Abstract: Initially described as an ancient and highly conserved catabolic biofunction, autophagy plays a significant role in disease pathogenesis and progression. As the bioactive ingredient of Salvia miltiorrhiza, tanshinone has recently shown profound effects in alleviating… read more here.
Keywords: autophagy medicinal; advances tanshinone; regulating autophagy; medicinal research ... See more keywords