Precision medicine for genetic epilepsy on the horizon: Recent advances, present challenges, and suggestions for continued progress
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DOI: 10.1111/epi.17332
Abstract: The genetic basis of many epilepsies is increasingly understood, giving rise to the possibility of precision treatments tailored to specific genetic etiologies. Despite this, current medical therapy for most epilepsies remains imprecise, aimed primarily at… read more here.
Keywords: genetic epilepsy; medicine genetic; precision medicine; medicine ... See more keywords
Pitfalls in developing precision medicine for genetic epilepsy
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DOI: 10.1212/wnl.0000000000004774
Abstract: The KCNT1 gene encodes a sodium-gated potassium channel subunit, which modulates hyperpolarization after repetitive neural firing.1 In 2012, mutations in KCNT1 were discovered in the familial focal epilepsy syndrome, autosomal dominant nocturnal frontal lobe epilepsy… read more here.
Keywords: epilepsy; medicine; precision medicine; medicine genetic ... See more keywords
Ethical Considerations in Precision Medicine and Genetic Testing in Internal Medicine Practice: A Position Paper From the American College of Physicians
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DOI: 10.7326/m22-0743
Abstract: This American College of Physicians position paper aims to inform ethical decision making for the integration of precision medicine and genetic testing into clinical care. Although the positions are primarily intended for practicing physicians, they… read more here.
Keywords: genetic testing; medicine genetic; precision medicine; american college ... See more keywords