Comparison of Methods for Estimating Unbound Intracellular-to-Medium Concentration Ratios in Rat and Human Hepatocytes Using Statins
Sign Up to like & getrecommendations! Published in 2017 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.116.074823
Abstract: It is essential to estimate concentrations of unbound drugs inside the hepatocytes to predict hepatic clearance, efficacy, and toxicity of the drugs. The present study was undertaken to compare predictability of the unbound hepatocyte-to-medium concentration… read more here.
Keywords: medium; concentration ratios; membrane; concentration ... See more keywords
Analgesic effects of different concentrations of ropivacaine in transversalis fascia plane block during laparotomy
Sign Up to like & getrecommendations! Published in 2022 at "BMC Anesthesiology"
DOI: 10.1186/s12871-022-01595-8
Abstract: Objective To explore the analgesic effects of different concentrations of ropivacaine in transversalis fascia plane (TFP) block during laparotomy. Methods Ninety patients who underwent laparotomy admitted to our hospital from March 2019 to March 2020… read more here.
Keywords: medium concentration; concentration; concentration group; high concentration ... See more keywords