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Published in 2019 at "Cancers"
DOI: 10.3390/cancers11091252
Abstract: Colorectal rhabdoid carcinomas (CRbCs) are very rare and aggressive cancers. The BRAF mutation and CpG island methylator phenotype have been reported to be common features of CRbCs. This study reviews the literature about CRbCs and…
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Keywords:
poorly differentiated;
medullary carcinomas;
colorectal rhabdoid;
braf mutation ... See more keywords
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Published in 2022 at "Cancers"
DOI: 10.3390/cancers14205044
Abstract: Simple Summary Renal medullary carcinomas (RMC) are aggressive tumors of the kidneys, characterized by a loss of SMARCB1. As the tumors, arising predominantly in young males with sickle cell trait, are very rare and no…
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Keywords:
methylation;
renal medullary;
nephrogenesis;
medullary carcinomas ... See more keywords
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Published in 2019 at "eLife"
DOI: 10.7554/elife.44161
Abstract: Renal medullary carcinoma (RMC) is a rare and deadly kidney cancer in patients of African descent with sickle cell trait. We have developed faithful patient-derived RMC models and using whole-genome sequencing, we identified loss-of-function intronic…
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Keywords:
smarcb1 loss;
loss;
carcinomas depend;
renal medullary ... See more keywords