Concurrent paediatric medulloblastoma and Chiari I malformation with syringomyelia
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DOI: 10.1007/s00381-017-3413-2
Abstract: Dear Editor: The concurrence of posterior fossa medulloblastoma and Chiari 1 malformation with syringomyelia in a paediatric patient is extremely rare. At present, the existence of a pathophysiological relationship between these two conditions remains unknown.… read more here.
Keywords: posterior fossa; medulloblastoma chiari; medulloblastoma; malformation syringomyelia ... See more keywords
Letter to the editor Management and outcome of treating pediatric medulloblastoma
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DOI: 10.1007/s00381-018-3795-9
Abstract: Dear Editor: Reading with interest the manuscript Management and outcomes of treating pediatric medulloblastoma: an eight years experience in an Iranian pediatric center [1], Dr. Mehrvar and the group of researchers have tried to highlight… read more here.
Keywords: outcome; medulloblastoma; editor; management ... See more keywords
Radiation-induced spinal cord glioblastoma subsequent to treatment of medulloblastoma: case report
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DOI: 10.1007/s00381-020-04817-x
Abstract: Medulloblastomas are one of the most common malignant pediatric brain tumors. Therapy has evolved into multimodality treatments consisting of surgery, radiation, and adjuvant chemotherapy. While craniospinal radiation remains standard for patients older than 3 years… read more here.
Keywords: radiation induced; treatment; medulloblastoma; radiation ... See more keywords
Benign skull and subdural lesions in patients with prior medulloblastoma therapy
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DOI: 10.1007/s00381-020-04874-2
Abstract: To report on our institutional cohort of patients and review the literature of medulloblastoma patients who developed skull/subdural-based lesions following treatment. Following institutional review board (IRB) approval, we retrospectively reviewed the medical records of four… read more here.
Keywords: skull subdural; subdural lesions; medulloblastoma; benign skull ... See more keywords
A novel finding of an IDH2 mutation in an interesting adult Sonic Hedgehog mutated medulloblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-019-03207-x
Abstract: We report the case of a 29-year-old female who presented with headaches and papilledema and found to have a right cerebellar T2/FLAIR hyperintense mass with restricted diffusion and minimal patchy enhancement resulting in fourth ventricular… read more here.
Keywords: adult; medulloblastoma; missense mutation; sonic hedgehog ... See more keywords
Clinical and molecular characterization of isolated M1 disease in pediatric medulloblastoma: experience from the German HIT-MED studies
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DOI: 10.1007/s11060-021-03913-5
Abstract: To evaluate the clinical impact of isolated spread of medulloblastoma cells into cerebrospinal fluid without additional macroscopic metastases (M1-only). The HIT-MED database was searched for pediatric patients with M1-only medulloblastoma diagnosed from 2000 to 2019.… read more here.
Keywords: disease; hit med; year pfs; medulloblastoma ... See more keywords
Medulloblastoma: Improved survival in recent decades. Unicentric experience
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DOI: 10.1016/j.anpede.2016.03.004
Abstract: Abstract Objective The aim of the study is to analyse variations in the treatment of medulloblastoma, the most common childhood brain tumour, and its impact on survival over the past two decades, as well as… read more here.
Keywords: decades unicentric; improved survival; medulloblastoma; recent decades ... See more keywords
Proteome and miRNome profiling of microvesicles derived from medulloblastoma cell lines with stem-like properties reveals biomarkers of poor prognosis
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research"
DOI: 10.1016/j.brainres.2020.146646
Abstract: Primary central nervous system (CNS) tumors are the most common deadly childhood cancer. Several patients with medulloblastoma experience local or metastatic recurrences after standard treatment, a condition associated with very poor prognosis. Current neuroimaging techniques… read more here.
Keywords: poor prognosis; mir; medulloblastoma; medulloblastoma cells ... See more keywords
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy.
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DOI: 10.1016/j.jcyt.2019.06.009
Abstract: BACKGROUND Medulloblastoma is the most common malignant brain tumor in childhood and adolescence. Although some patients present with distinct genetic alterations, such as mutated TP53 or MYC amplification, pediatric medulloblastoma is a tumor entity with… read more here.
Keywords: mutational load; low mutational; medulloblastoma; specific cell ... See more keywords
Urinary protein biomarkers for pediatric medulloblastoma.
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DOI: 10.1016/j.jprot.2020.103832
Abstract: OBJECTIVE To identify candidate urinary protein biomarkers to distinguish medulloblastoma (MB) patients from healthy patients or benign brain disease control patients. METHODS The tandem mass tag (TMT)-labeled quantitative proteomics approach was used to identify differential… read more here.
Keywords: control patients; control; medulloblastoma; disease ... See more keywords
In silico analysis of long non-coding RNAs in medulloblastoma and its subgroups
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DOI: 10.1016/j.nbd.2020.104873
Abstract: Medulloblastoma is the most common malignant pediatric brain tumor with high fatality rate. Recent large-scale studies utilizing genome-wide technologies have sub-grouped medulloblastomas into four major subgroups: wingless (WNT), sonic hedgehog (SHH), group 3, and group… read more here.
Keywords: coding rnas; analysis; medulloblastoma; long non ... See more keywords