Articles with "medulloblastoma pathogenesis" as a keyword



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Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.

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Published in 2018 at "Cell reports"

DOI: 10.1016/j.celrep.2018.01.018

Abstract: Sonic hedgehog (Shh) determines cerebellar granule cell (GC) progenitor proliferation and medulloblastoma pathogenesis. However, the pathways regulating GC progenitors during embryogenesis before Shh production by Purkinje neurons and their roles in tumorigenesis remain unclear. The… read more here.

Keywords: gpr161; protein coupled; pathway; shh ... See more keywords