MBRS-29. PROSPECTIVE MOLECULAR PROFILING IN PEDIATRIC MEDULLOBLASTOMA PATIENTS ENROLLED ON THE “HEAD START 4” PROTOCOL
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.544
Abstract: Abstract Medulloblastoma is the most common malignant embryonal brain tumor in children with only modest improvements in outcomes achieved over the last 20 years. The implementation of irradiation-avoiding strategies, including trials by the “Head Start”… read more here.
Keywords: patients enrolled; medulloblastoma patients; head start; medulloblastoma ... See more keywords
Predictors of Posterior Fossa Syndrome: Results From an International Multicenter Cohort Study of Molecularly Characterized Medulloblastoma Patients
Sign Up to like & getrecommendations! Published in 2019 at "Neurosurgery"
DOI: 10.1093/neuros/nyz310_198
Abstract: Posterior Fossa Syndrome (PFS) is a common complication following surgical resection of pediatric posterior fossa tumors. PFS is characterized by a combination of mutism, ataxia, and other behavioral symptoms that typically improves within weeks to… read more here.
Keywords: molecularly characterized; medulloblastoma patients; posterior fossa; cohort ... See more keywords
Abstract 5826: Essential role for cyclic-AMP responsive element binding protein 1 (CREB1) phosphorylation in the survival of medulloblastoma patients
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-5826
Abstract: Prognosis for recurrent medulloblastoma patients is extremely poor, with a median survival of 26.8 months. Treatment options for recurrent medulloblastoma patients are limited and ineffective due to resistance to chemotherapeutic agents and radiotherapy. Therefore, more… read more here.
Keywords: medulloblastoma patients; medulloblastoma; creb; cell ... See more keywords
Tumor-Associated Macrophages Correlate With Prognosis in Medulloblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.893132
Abstract: Purpose Macrophage polarization plays an essential role in the tumor microenvironment of brain tumors. However, the role of tumor-associated macrophages (TAMs) in medulloblastoma still remains controversial. Thus, we investigated the distribution of macrophages in medulloblastoma… read more here.
Keywords: macrophages correlate; medulloblastoma; associated macrophages; medulloblastoma patients ... See more keywords