The transcription factor MEF2A plays a key role in the differentiation/maturation of rat neural stem cells into neurons
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and Biophysical Research Communications"
DOI: 10.1016/j.bbrc.2018.04.125
Abstract: Neural stem cells (NSCs) are self-renewing multipotent stem cells that can be proliferated in vitro and differentiated into neuronal and/or glial lineages, making them an ideal model to study the processes involved in neuronal differentiation.… read more here.
Keywords: mef2a; transcription factor; differentiation; stem cells ... See more keywords
lncRNA MIR155HG Accelerates the Progression of Sepsis via Upregulating MEF2A by Sponging miR-194-5p.
Sign Up to like & getrecommendations! Published in 2021 at "DNA and cell biology"
DOI: 10.1089/dna.2021.0038
Abstract: Long noncoding RNA MIR155HG exerts important effects in the progression of multiple diseases. This study investigated the functions of MIR155HG in sepsis development. Blood samples were collected from 28 patients with sepsis and 28 without… read more here.
Keywords: sepsis; raw 264; mef2a; cell ... See more keywords
MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells
Sign Up to like & getrecommendations! Published in 2019 at "BMC Molecular Biology"
DOI: 10.1186/s12867-019-0125-z
Abstract: BackgroundMyocyte enhancer factor 2A (MEF2A) plays an important role in cell proliferation, differentiation and survival. Functional deletion or mutation in MEF2A predisposes individuals to cardiovascular disease mainly caused by vascular endothelial dysfunction. However, the effect… read more here.
Keywords: mef2a; senescence; inflammation; expression ... See more keywords
MEF2A Is the Trigger of Resveratrol Exerting Protection on Vascular Endothelial Cell
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.775392
Abstract: Both resveratrol and myocyte enhancer factor 2A (MEF2A) may protect vascular endothelial cell (VEC) through activating the expression of SIRT1. However, the relationship between resveratrol and MEF2A is unclear. We aimed to investigate the deeper… read more here.
Keywords: mef2a; vascular endothelial; endothelial cell; silencing mef2a ... See more keywords
MiRNA-615-3p Alleviates Oxidative Stress Injury of Human Cardiomyocytes Via PI3K/Akt Signaling by Targeting MEF2A
Sign Up to like & getrecommendations! Published in 2022 at "Anatolian Journal of Cardiology"
DOI: 10.5152/anatoljcardiol.2021.901
Abstract: Background Myocardial infarction, a coronary heart disease, is a serious hazard to human health. Cardiomyocyte oxidative stress and apoptosis have been considered as the main causes of myocardial infarction. Here, we aimed to investigate the… read more here.
Keywords: apoptosis; mef2a; oxidative stress; human cardiomyocytes ... See more keywords