Mefenamic Acid Attenuates Chronic Alcohol Induced Cognitive Impairment in Zebrafish: Possible Role of Cholinergic Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2554-3
Abstract: Based on the scientific evidence supporting the neuroinflammatory response contributes the cognitive impairment associated with chronic alcoholism and the neuroprotective actions of mefenamic acid with reversal of memory loss and brain inflammation in mice, this study… read more here.
Keywords: mefenamic acid; cognitive impairment; acid; alcohol ... See more keywords
Biodegradability of fluoxetine, mefenamic acid, and metoprolol using different microbial consortiums
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-017-8413-y
Abstract: The biodegradation of fluoxetine, mefenamic acid, and metoprolol using ammonium-nitrite-oxidizing consortium, nitrite-oxidizing consortium, and heterotrophic biomass was evaluated in batch tests applying different retention times. The ammonium-nitrite-oxidizing consortium presented the highest biodegradation percentages for mefenamic… read more here.
Keywords: acid metoprolol; consortium; biodegradation; mefenamic acid ... See more keywords
Novel silver(I) complexes bearing mefenamic acid and pyridine derivatives: Synthesis, chemical characterization and in vitro anticancer evaluation
Sign Up to like & getrecommendations! Published in 2019 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2019.05.008
Abstract: Abstract Two Ag(I) complexes [Ag2(μ-mef)2(2-pymet)2] 1, [Ag2(μ-mef)2(2-pyet)2] 2 containing mefenamic acid, 2-pyridinemethanol and 2-pyridineethanol were synthesized and characterized by using SCXRD, FT-IR, elemental and thermal analysis techniques. The complex 1 was synthesized as a single… read more here.
Keywords: mefenamic acid; complexes bearing; bearing mefenamic; silver complexes ... See more keywords
Synthesis, characterization, antioxidant and antidiabetic studies of Cu(II) and Zn(II) complexes of tolfenamic acid/mefenamic acid with 1-methylimidazole
Sign Up to like & getrecommendations! Published in 2020 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2020.119942
Abstract: Abstract Cu(II) and Zn(II) complexes of tolfenamic acid (tolf) and mefenamic acid (mef) with 1-methylimidazole (1-mdz) formulated as [Cu(tolf)2(1-mdz)2] (1) [Cu(mef)2(1-mdz)2]·H2O (2) and [Zn2(tolf)4(1-mdz)2] (3) were synthesized and characterized by elemental analysis, spectroscopic techniques and… read more here.
Keywords: mefenamic acid; complexes tolfenamic; geometry; tolfenamic acid ... See more keywords
Mefenamic acid solid dispersions: Impact of formulation composition on processing parameters, product properties and performance.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2022.121505
Abstract: The objective of this study was to develop an immediate release (IR), crystalline solid dispersion (CSD) formulation of Mefenamic acid (MFA) by hot-melt-extrusion (HME) and assess the impact of drug loading on process parameters, product… read more here.
Keywords: product; drug loading; drug; formulation ... See more keywords
Impact of the central atom on human genomic DNA and human serum albumin binding properties in analogous Zn(II) and Cd(II) complexes with mefenamic acid
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.03.078
Abstract: Abstract Two novel complexes of Zn(II) and Cd(II) with Hmef (mefenamic acid) and bapen (N,N′-bis(3-aminopropyl)ethylenediamine) ligand were synthesized and characterized by infrared spectroscopy, elemental, thermal and single-crystal X-ray structure analysis. Both complexes form molecular structure… read more here.
Keywords: dna; mefenamic acid; central atom; human serum ... See more keywords
Microwave assisted amberlite-IRA-402 (OH) ion exchange resin catalyzed synthesis of new benzoxazole scaffolds derived from antiinflammatory drugs aceclofenac and mefenamic acid as potential therapeutic agents for inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.127092
Abstract: Abstract An efficient microwave assisted synthesis of 2-substituted benzoxazole derivatives from antiinflammatory drugs aceclofenac and mefenamic acid using amberlite-IRA-402 (OH) ion exchange resin as a base catalyst were reported. The synthesized compounds were purified and… read more here.
Keywords: amberlite ira; antiinflammatory drugs; mefenamic acid; aceclofenac mefenamic ... See more keywords
Structural features of nickel(II) mixed ligand complexes with mefenamic acid and nitrogen donor ligands
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.129632
Abstract: Abstract The reaction between Ni(NO3)2.6H2O and the non-steroidal anti-inflammatory mefenamic acid (2-[(2,3-dimethylphenyl)amino]benzoic acid), in the presence of various nitrogen donor ligands (imidazole, 2-methylimidazole, pyridine, and nicotinamide) have resulted in the formation of four novel mixed… read more here.
Keywords: nitrogen donor; donor ligands; mefenamic acid; mixed ligand ... See more keywords
Characterization of human sulfotransferases catalyzing the formation of p-cresol sulfate and identification of mefenamic acid as a potent metabolism inhibitor and potential therapeutic agent for detoxification.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2021.115553
Abstract: p-Cresol sulfate, the primary metabolite of p-cresol, is a uremic toxin that has been associated with toxicities and mortalities. The study objectives were to i) characterize the contributions of human sulfotransferases (SULT) catalyzing p-cresol sulfate… read more here.
Keywords: mefenamic acid; formation cresol; cresol sulfate; cresol ... See more keywords
Ultrasound assisted crystallization of mefenamic acid: Effect of operating parameters and comparison with conventional approach.
Sign Up to like & getrecommendations! Published in 2017 at "Ultrasonics sonochemistry"
DOI: 10.1016/j.ultsonch.2016.08.001
Abstract: The current work investigates the application of low intensity ultrasonic irradiation for improving the cooling crystallization of Mefenamic Acid for the first time. The crystal shape and size has been analyzed with the help of… read more here.
Keywords: mefenamic acid; crystallization; conventional approach; ultrasound assisted ... See more keywords
Quantum Chemical Study on Mefenamic Acid Polymorphic Forms
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c06967
Abstract: Three polymorphic structures of mefenamic acid, which is a very popular drug, have been studied using quantum chemical methods. It has been shown that the centrosymmetric dimer formed due to two O–H···O hydrogen bonds is… read more here.
Keywords: structure; polymorphic forms; energy; mefenamic acid ... See more keywords