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   Articles with "meg3" as a keyword



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Long noncoding RNA MEG3 inhibits oral squamous cell carcinoma progression via GATA3

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recommendations! Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13532

Abstract: Oral squamous cell carcinoma (OSCC) accounts for about 90% of oral cancers. Expression of the long noncoding RNA (lncRNA) maternally expressed 3 (MEG3) has previously been reported to be downregulated in OSCC, and its overexpression… read more here.

Keywords: cell carcinoma; squamous cell; long noncoding; gata3 ... See more keywords
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Silencing of MEG3 inhibited ox‐LDL‐induced inflammation and apoptosis in macrophages via modulation of the MEG3/miR‐204/CDKN2A regulatory axis

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recommendations! Published in 2019 at "Cell Biology International"

DOI: 10.1002/cbin.11105

Abstract: Atherosclerosis (AS) is one of the most common chronic inflammatory diseases and a major cause of morbidity and mortality. However, the underlying molecular mechanisms of the progression of AS are still largely unknown. Increasing evidence… read more here.

Keywords: meg3; cells treated; cdkn2a; mir 204 ... See more keywords
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LncRNA MEG3 suppresses migration and promotes apoptosis by sponging miR‐548d‐3p to modulate JAK–STAT pathway in oral squamous cell carcinoma

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recommendations! Published in 2019 at "IUBMB Life"

DOI: 10.1002/iub.2012

Abstract: Oral squamous cell carcinoma (OSCC) is a lethal malignancy and its prognosis remains dismal. Thus, a deeper understanding of the mechanisms is needed to provide a new insight for new therapies. It has been reported… read more here.

Keywords: meg3; stat pathway; mir 548d; jak stat ... See more keywords
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Overexpression of Long Non‐Coding RNA MEG3 Inhibits Proliferation of Hepatocellular Carcinoma Huh7 Cells via Negative Modulation of miRNA‐664

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recommendations! Published in 2017 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.26018

Abstract: Evidence is accumulating that long non‐coding RNAs (lncRNAs) are involved in human tumorigenesis and dysregulated in many cancers, including hepatocellular carcinoma (HCC). Because lncRNAs can regulate essential pathways that contribute to tumor initiation and progression… read more here.

Keywords: hepatocellular carcinoma; overexpression; meg3; long non ... See more keywords
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Long noncoding RNA MEG3 regulates rheumatoid arthritis by targeting NLRC5

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recommendations! Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.28126

Abstract: Rheumatoid arthritis (RA) is one of the chronic systemic autoimmune diseases that cardinally affect the joints. Many people all over the world suffer from the disease. Fibroblast‐like synoviocytes (FLSs) play a significant role in the… read more here.

Keywords: long noncoding; meg3; noncoding rna; cfa induced ... See more keywords
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LncRNA-MEG3 Regulates the Inflammatory Responses and Apoptosis in Porcine Alveolar Macrophages Infected with Haemophilus parasuis Through Modulating the miR-210/TLR4 Axis.

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recommendations! Published in 2021 at "Current microbiology"

DOI: 10.1007/s00284-021-02590-x

Abstract: Haemophilus parasuis (H. parasuis, HPS) can elicit serious inflammatory responses and cause enormous economic loss to swine industry worldwide. However, the factors responsible for systemic infection and inflammatory responses of HPS have not yet been… read more here.

Keywords: responses apoptosis; inflammatory responses; meg3; lncrna meg3 ... See more keywords
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Long non-coding RNA MEG3 inhibits adipogenesis and promotes osteogenesis of human adipose-derived mesenchymal stem cells via miR-140-5p

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recommendations! Published in 2017 at "Molecular and Cellular Biochemistry"

DOI: 10.1007/s11010-017-3015-z

Abstract: AbstractlncRNAs are an emerging class of regulators involved in multiple biological processes. MEG3, an lncRNA, acts as a tumor suppressor, has been reported to be linked with osteogenic differentiation of MSCs. However, limited knowledge is… read more here.

Keywords: meg3; adipogenesis; differentiation; hascs ... See more keywords

Long non-coding RNA MEG3 regulates proliferation, apoptosis, and autophagy and is associated with prognosis in glioma

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recommendations! Published in 2018 at "Journal of Neuro-Oncology"

DOI: 10.1007/s11060-018-2874-9

Abstract: PurposeAccumulating evidence indicates that dysregulated long noncoding RNAs (lncRNAs) play critical roles in tumorigenesis and cancer progression. LncRNA-maternally expressed gene 3 (MEG3) has been shown to be involved in the initiation and development of several… read more here.

Keywords: apoptosis autophagy; proliferation apoptosis; meg3; glioma ... See more keywords
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Long non-coding RNA MEG3 inhibits chondrogenic differentiation of synovium-derived mesenchymal stem cells by epigenetically inhibiting TRIB2 via methyltransferase EZH2.

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recommendations! Published in 2019 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2019.109379

Abstract: Osteoarthritis (OA) is a highly prevalent skeletal disease. Mesenchymal stem cell-derived cartilage tissue engineering is a clinical method used for OA treatment. Investigations on the molecular regulatory mechanisms of the chondrogenic differentiation of synovium-derived mesenchymal… read more here.

Keywords: meg3; chondrogenic differentiation; trib2; mesenchymal stem ... See more keywords
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LncRNA MEG3 reverses CCl4-induced liver fibrosis by targeting NLRC5.

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recommendations! Published in 2021 at "European journal of pharmacology"

DOI: 10.1016/j.ejphar.2021.174462

Abstract: Liver fibrosis is a persistent pathological repair of chronic liver injury, which is characterized by excessive deposition of collagen-dominated extracellular matrix (ECM). It is well known that hepatic fibrosis can be reversed in the absence… read more here.

Keywords: targeting nlrc5; meg3; fibrosis; lncrna meg3 ... See more keywords

Knockdown of long noncoding RNA MEG3 impairs VEGF-stimulated endothelial sprouting angiogenesis via modulating VEGFR2 expression in human umbilical vein endothelial cells.

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recommendations! Published in 2018 at "Gene"

DOI: 10.1016/j.gene.2018.01.072

Abstract: Long noncoding RNAs is a novel class of RNA molecules, which is closely related to the occurrence and development of human disease. Recent studies have highlighted the importance of MEG3 in angiogenesis and the maintenance… read more here.

Keywords: long noncoding; meg3; angiogenesis; vegfr2 expression ... See more keywords