SATB1 chromatin loops regulate Megakaryocyte/Erythroid Progenitor Expansion by facilitating HSP70 and GATA1 induction.
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DOI: 10.1093/stmcls/sxad025
Abstract: Diamond Blackfan Anemia (DBA) is an inherited bone marrow failure syndrome associated with severe anemia, congenital malformations and increased risk of developing cancer. The chromatin-binding SATB1 is downregulated in Megakaryocyte/Erythroid Progenitors (MEPs) in patients and… read more here.
Keywords: megakaryocyte erythroid; hsp70; gata1 induction; chromatin loops ... See more keywords