Megestrol acetate for cachexia–anorexia syndrome. A systematic review
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12292
Abstract: In 1993, megestrol acetate (MA) was approved by the US Food and Drug Administration for the treatment of anorexia, cachexia, or unexplained weight loss in patients with acquired immunodeficiency syndrome. The mechanism by which MA… read more here.
Keywords: megestrol acetate; systematic review; cachexia; adverse events ... See more keywords
Pterostilbene, a natural phenolic compound, synergizes the antineoplastic effects of megestrol acetate in endometrial cancer
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12922-2
Abstract: Endometrial cancer is the most common gynecologic cancer in the United States and its incidence and mortality has been rising over the past decade. Few treatment options are available for patients with advanced and recurring… read more here.
Keywords: acetate endometrial; pterostilbene; endometrial cancer; cancer ... See more keywords
Megestrol Acetate Induces Declarative Memory Changes and Cortisol Suppression in Healthy Volunteers
Sign Up to like & getrecommendations! Published in 2018 at "Dementia and Geriatric Cognitive Disorders"
DOI: 10.1159/000490789
Abstract: Background: The effects of the glucocorticoid and progesterone receptor agonist megestrol on declarative memory, and the ability of phenytoin to block these effects, were assessed. Methods: Healthy volunteers received each medication combination (placebo and megestrol,… read more here.
Keywords: declarative memory; cortisol suppression; healthy volunteers; megestrol acetate ... See more keywords
Treating anorexia in people with advanced cancer. a randomised, double blind, controlled trial of megestrol acetate, dexamethasone or placebo.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.10020
Abstract: 10020Background: This multi-site, double blind, parallel arm, fixed dose phase III study compared megestrol acetate 480 mg/day, dexamethasone 4 mg/day and placebo for their net short-term effect on... read more here.
Keywords: dexamethasone; megestrol acetate; double blind; treating anorexia ... See more keywords
Nanoemulsions Containing Megestrol Acetate: Development, Characterization, and Stability Evaluation
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02289-7
Abstract: Many active pharmaceutical ingredients (API) are poorly soluble in water and their low oral bioavailability is a major hindrance to their potential use. Megestrol acetate (MGA) is insoluble in water and its oral absorption is… read more here.
Keywords: stability; megestrol acetate; mga; characterization ... See more keywords