Articles with "meht" as a keyword



Enhancing therapeutic efficacy in triple‐negative breast cancer and melanoma: synergistic effects of modulated electro‐hyperthermia (mEHT) with NSAIDs especially COX‐2 inhibition in in vivo models

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Published in 2024 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13585

Abstract: Triple‐negative breast cancer (TNBC) is a leading cause of cancer mortality and lacks modern therapy options. Modulated electro‐hyperthermia (mEHT) is an adjuvant therapy with demonstrated clinical efficacy for the treatment of various cancer types. In… read more here.

Keywords: cancer; breast cancer; meht; negative breast ... See more keywords

Relationship between Energy Dosage and Apoptotic Cell Death by Modulated Electro-Hyperthermia

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-65823-2

Abstract: Modulated electro-hyperthermia (mEHT) is a form of mild hyperthermia (HT) used for cancer treatment. The principle utility of HT is the ability not only to increase cell temperature, but also to increase blood flow and… read more here.

Keywords: phase; temperature; apoptosis; power ... See more keywords

The effect of modulated electro-hyperthermia on local disease control in HIV-positive and -negative cervical cancer women in South Africa: Early results from a phase III randomised controlled trial

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Published in 2019 at "PLoS ONE"

DOI: 10.1371/journal.pone.0217894

Abstract: Background The global burden of cervical cancer remains high with the highest morbidity and mortality rates reported in developing countries. Hyperthermia as a chemo- and radiosensitiser has shown to improve treatment outcomes. This is an… read more here.

Keywords: trial; control; treatment; cervical cancer ... See more keywords

Modulated electro-hyperthermia-enhanced liposomal drug uptake by cancer cells

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Published in 2019 at "International Journal of Nanomedicine"

DOI: 10.2147/ijn.s188791

Abstract: Purpose Modulated electro-hyperthermia (mEHT) stands to be a significant technological advancement in the hyperthermia field, utilizing autofocusing electromagnetic power on the cell membrane to create massive apoptosis. Since mEHT possesses the unique ability to excite… read more here.

Keywords: cancer cells; meht; hyperthermia; drug uptake ... See more keywords

Effects of Modulated Electro-Hyperthermia (mEHT) on Two and Three Year Survival of Locally Advanced Cervical Cancer Patients

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14030656

Abstract: Simple Summary More than 80% of global cervical cancer cases and deaths occur in Low-to-Middle-Income Countries. Improving the efficacy of treatments without increasing the costs in these regions is therefore imperative. The aim of our… read more here.

Keywords: cervical cancer; survival; meht; modulated electro ... See more keywords

Long-Term Feasibility of 13.56 MHz Modulated Electro-Hyperthermia-Based Preoperative Thermoradiochemotherapy in Locally Advanced Rectal Cancer

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14051271

Abstract: Simple Summary We demonstrated that a 13.56 MHz modulated electro-hyperthermia (mEHT) boost is feasible in neoadjuvant treatment for rectal cancer. Herein, we attempted to present the long-term results for this phase 2 trial. Although there… read more here.

Keywords: modulated electro; electro hyperthermia; hyperthermia; rectal cancer ... See more keywords

Modulated Electro-Hyperthermia Accelerates Tumor Delivery and Improves Anticancer Activity of Doxorubicin Encapsulated in Lyso-Thermosensitive Liposomes in 4T1-Tumor-Bearing Mice

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Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms25063101

Abstract: Modulated electro-hyperthermia (mEHT) is an adjuvant cancer therapy that enables tumor-selective heating (+2.5 °C). In this study, we investigated whether mEHT accelerates the tumor-specific delivery of doxorubicin (DOX) from lyso-thermosensitive liposomal doxorubicin (LTLD) and improves… read more here.

Keywords: mice; dox; meht; delivery ... See more keywords