Mass Spectrometric Analysis of Meibomian Gland Lipids.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1410-5_11
Abstract: The precorneal tear film keeps the eye surface moist and helps to maintain normal eye function. The outermost lipid layer of the tear film, which attenuates tear film evaporation, contains meibum secreted from the meibomian… read more here.
Keywords: tear film; analysis; lipids mass; meibomian gland ... See more keywords
Dry eye and meibomian gland dysfunction in pseudophakic bullous keratopathy
Sign Up to like & getrecommendations! Published in 2018 at "International Ophthalmology"
DOI: 10.1007/s10792-018-0824-3
Abstract: PurposeTo evaluate dry eye tests and meibography of patients with pseudophakic bullous keratopathy (PBK).Materials and MethodsThirty-seven patients with PBK were included. The eyes with PBK were compared with the normal pseudophakic fellow eyes. All patients… read more here.
Keywords: meibomian gland; bullous keratopathy; gland; dry eye ... See more keywords
Analysis of Cytokine Levels in Tears and Clinical Correlations After Intense Pulsed Light Treating Meibomian Gland Dysfunction.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2017.08.021
Abstract: PURPOSE To investigate the change from baseline of inflammatory markers in tears of dry eye disease (DED) subjects owing to meibomian gland dysfunction (MGD) after intense pulsed light (IPL) treatment and meibomian gland expression (MGE)… read more here.
Keywords: meibomian gland; pulsed light; treatment; intense pulsed ... See more keywords
Effect of brimonidine, an &agr;2 adrenergic agonist, on human meibomian gland epithelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2018.02.009
Abstract: ABSTRACT We recently discovered that the anti‐glaucoma pharmaceuticals timolol, a &bgr; adrenergic antagonist, and pilocarpine, a cholinergic compound, negatively influence the morphology, proliferative capacity and survival of human meibomian gland epithelial cells (HMGECs). We hypothesize… read more here.
Keywords: meibomian gland; epithelial cells; agr adrenergic; human meibomian ... See more keywords
Establishment of a human meibomian gland carcinoma cell model and analysis of differently expressed genes.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental eye research"
DOI: 10.1016/j.exer.2022.108983
Abstract: Meibomian gland carcinoma (MGC) is a malignant eyelid tumor with a high malignancy degree and poor prognosis. However, the lack of suitable cell and animal models has limited the study of MGC pathogenesis. In the… read more here.
Keywords: expressed genes; mgc cells; cell; meibomian gland ... See more keywords
Prevalence of meibomian gland dysfunction at the time of cataract surgery.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of cataract and refractive surgery"
DOI: 10.1016/j.jcrs.2017.10.050
Abstract: PURPOSE To determine the incidence of meibomian gland dysfunction and quantify subjective dry-eye symptoms in cataract surgery candidates. SETTING Brest University Hospital, Brest, France. DESIGN Prospective case series. METHODS Patients having cataract surgery between November… read more here.
Keywords: meibomian gland; lipid layer; gland; gland dysfunction ... See more keywords
Influence of Meibomian Gland Dysfunction and Friction-Related Disease on the Severity of Dry Eye.
Sign Up to like & getrecommendations! Published in 2018 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2018.01.025
Abstract: PURPOSE To evaluate the effect of meibomian gland dysfunction (MGD) and friction-related disease (FRD) on the severity of dry eye disease (DED). DESIGN Cross-sectional observational study. PARTICIPANTS This study enrolled 449 patients with DED (63… read more here.
Keywords: meibomian gland; disease; tbut; gland dysfunction ... See more keywords
Comprehensive profiling of Asian and Caucasian meibomian gland secretions reveals similar lipidomic signatures regardless of ethnicity
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71259-5
Abstract: Meibum—a lipid secretion that is produced by Meibomian glands (MG) in a process termed meibogenesis—plays a critical role in ocular surface physiology. Abnormalities in the chemical composition of meibum were linked to widespread ocular pathologies—dry… read more here.
Keywords: meibomian gland; gland secretions; asian caucasian; profiling asian ... See more keywords
Pathophysiology of Meibomian Glands – An Overview
Sign Up to like & getrecommendations! Published in 2021 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2021.1905856
Abstract: ABSTRACT Purpose: The meibomian glands are located in the tarsal plate of the upper and lower eyelid and are responsible for the production of a lipid-rich secretion, the meibum, which forms the outer component of… read more here.
Keywords: meibomian gland; pathophysiology meibomian; meibomian glands; gland ... See more keywords
Meibomian Gland Dysfunction in Patients With Chemotherapy-Induced Lacrimal Drainage Obstruction
Sign Up to like & getrecommendations! Published in 2017 at "Cornea"
DOI: 10.1097/ico.0000000000001172
Abstract: Purpose: To investigate the relationship between chemotherapy-induced lacrimal drainage (LD) obstruction and obstructive meibomian gland dysfunction. Methods: Twenty patients who had received chemotherapy were divided into 2 groups, according to the presence of LD obstruction:… read more here.
Keywords: meibomian gland; obstruction; group; chemotherapy induced ... See more keywords
Prevalence of Meibomian Gland Atrophy in a Pediatric Population
Sign Up to like & getrecommendations! Published in 2018 at "Cornea"
DOI: 10.1097/ico.0000000000001476
Abstract: Purpose: To report the prevalence of meibomian gland atrophy and gland tortuosity in a pediatric population. Methods: Participants who presented with no history of dry eye disease or meibomian gland dysfunction were recruited from the… read more here.
Keywords: pediatric population; meibomian gland; gland atrophy; gland ... See more keywords