A spectroscopic approach to measuring meibum lipid composition and conformation in donors with Sjӧgren's syndrome.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental eye research"
DOI: 10.1016/j.exer.2021.108713
Abstract: Patients with Sjӧgren's syndrome (SS) have dry eye associated with meibomian gland dysfunction (MGD). The meibum from donors with dry eye due to MGD but without SS (MMGD) presents with lower levels of cholesteryl ester,… read more here.
Keywords: gren syndrome; meibum donors; conformation; meibum ... See more keywords
Comprehensive lipid analysis of human meibum and tears
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DOI: 10.1038/s41598-025-23048-1
Abstract: Abnormalities in the tear film lipid layer, which plays a critical role in preventing water evaporation and protecting the corneal surface, lead to dry eye disease. The lipids in this layer include both meibum lipids… read more here.
Keywords: lipid analysis; composition; meibum tears; meibum ... See more keywords
Differences in Meibum and Tear Lipid Composition and Conformation.
Sign Up to like & getrecommendations! Published in 2019 at "Cornea"
DOI: 10.1097/ico.0000000000002095
Abstract: PURPOSE The compositional, structural, and functional relationships of meibum may provide insights into the loss of tear film stability. Although the conformation of meibum lipids has been studied rigorously, that of tear lipids has not.… read more here.
Keywords: lipid composition; conformation; tear film; meibum ... See more keywords
[Possibilities of optical fluorescence spectral decomposition of meibum].
Sign Up to like & getrecommendations! Published in 2025 at "Vestnik oftalmologii"
DOI: 10.17116/oftalma202514105129
Abstract: OBJECTIVE The is study evaluated the possibilities of using optical fluorescence to determine the components of meibum. MATERIAL AND METHODS Meibum samples from 16 volunteers were analyzed using fluorescence spectroscopy in the visible optical range.… read more here.
Keywords: spectroscopy; spectroscopy visible; meibum; fluorescence ... See more keywords
Comparative Transcriptomic and Lipidomic Analyses of Human Male and Female Meibomian Glands Reveal Common Signature Genes of Meibogenesis
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20184539
Abstract: Meibum is a lipid secretion that is produced by holocrine Meibomian glands (MGs). MGs are a specialized type of sebaceous glands that are embedded in the human eyelids. Chemically, meibum and sebum are different. A… read more here.
Keywords: meibum; meibomian glands; signature genes; genes meibogenesis ... See more keywords