The oncogenic role of meiosis-specific Aurora kinase C in mitotic cells.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2021.112803
Abstract: Aberrant expression of meiosis-specific genes in cancer has recently emerged as a driver of some cancer formation. Aurora kinase C (AURKC) is a member of the Aurora kinase family of proteins known to regulate chromosome… read more here.
Keywords: meiosis specific; aurora kinase; cancer cells; cancer ... See more keywords
The meiosis-specific Cdc20 family-member Ama1 promotes binding of the Ssp2 activator to the Smk1 MAP kinase
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e17-07-0473
Abstract: Smk1 is a meiosis-specific MAP kinase that is activated by a binding partner, Ssp2. This study shows that the meiosis-specific Cdc20 homologue, Ama1, triggers Ssp2/Smk1 complex formation at specialized meiotic membranes as nuclear segregation is… read more here.
Keywords: meiosis specific; map kinase; specific cdc20; meiosis ... See more keywords
Isc10, a meiosis-specific MAPK binding protein links the APC/C to Smk1 activation.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and cellular biology"
DOI: 10.1128/mcb.00097-20
Abstract: Smk1 is a meiosis-specific MAPK in yeast that controls spore differentiation. It is activated by a MAPK binding-protein, Ssp2, upon completion of the meiotic divisions. The activation of Smk1 by Ssp2 is positively regulated by… read more here.
Keywords: activation; isc10; mapk binding; specific mapk ... See more keywords
Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly
Sign Up to like & getrecommendations! Published in 2020 at "Life Science Alliance"
DOI: 10.26508/lsa.201900630
Abstract: The AAA+ protein Pch2 forms a biochemical complex with Orc1/ORC to suppress DNA break formation in the meiotic G2/prophase. Pch2 is a meiosis-specific AAA+ protein that controls several important chromosomal processes. We previously demonstrated that… read more here.
Keywords: meiosis specific; aaa; pch2 orc; orc ... See more keywords