Meiotic cells escape prolonged spindle checkpoint activity through kinetochore silencing and slippage.
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DOI: 10.1371/journal.pgen.1010707
Abstract: To prevent chromosome mis-segregation, a surveillance mechanism known as the spindle checkpoint delays the cell cycle if kinetochores are not attached to spindle microtubules, allowing the cell additional time to correct improper attachments. During spindle… read more here.
Keywords: slippage; checkpoint activity; meiotic cells; checkpoint ... See more keywords